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diagnosis differential classification hematology cryofibrinogenemia cryoglobulins cutaneous dermatologic gpa granulomatosis joint management nonpalpable pain polyangiitis purpura rash rashes sjogrens syndrome
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... Clinical triad of Palpable ... - 10% SLE or RA ... reticularis & skin ... classification #rheumatology
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Secondary: CTD: SLE, RA ... Vessel: Petechiae, Palpable ... Urticarial/LCV) - Cryoglobulinemic ... #skin #dermatology ... #rheumatology #
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... /HSP • Cryoglobulinemia ... Differential #Diagnosis #hematology ... #rheumatology # ... #dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... • Petechiae, Palpable ... • Petechiae • Palpable ... purpura • Mixed cryoglobulinemia ... rash #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Crohn's disease Palpable ... Hypersensitivity vasculitis ... gangrenosum • IBD • RA ... Sarcoidosis #dermatology ... differential #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis - Skin ... scleritis • Palpable ... purpura: strong sign ... -> causing palpable ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... ) • Palpable purpura ... / ANCA + MPO) Cryoglobulinemic ... macules, palpable ... Differential #Diagnosis #Rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Divided Into Two Types ... malignancies, vasculitis ... , sepsis or cryoglobulinemia ... Calciphylaxis • Cryoglobulinemia ... #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA ... ) • Cutaneous vasculitis ... : 2% Systemic Vasculitis ... : • 7%, Cryoglobulinemia ... Sjogrens #Syndrome #Rheumatology
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