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differential classification dermatology behcet cryoglobulinemia cryoglobulins dermatologic erythematosus fungal granulomatosis infections infectiousdiseases inflammatory iris lupus mycoses polyangiitis rash reconstitution signs
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
: • Immune Complex ... - GPA Cutaneous ... : • Behcet Disease ... • Cogan syndrome ... Vasculitis #skin
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... inflammation • Pauci-immune ... vasculitis Skin ... Rarely dominate the clinical ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Necrotizing, pauci-immune ... respiratory tracts Immune ... aphthous ulcers, cutaneous ... strong sign of cutaneous ... #rheumatology #
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... • Autoimmune diseases ... - GPA, EGPA, microscopic ... Henoch-Schönlein purpura) • Cutaneous ... classification #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... Differential Diagnosis ... Strong sign of cutaneous ... • Cogan syndrome ... #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... ) • Cutaneous Lesions ... (Clinical Dx). ... #diagnosis #management ... signs #symptoms #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... context of primary immune ... Clinical Features ... #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
salivary ducts Clinical ... ) • Cutaneous vasculitis ... : 2% Systemic Vasculitis ... #Rheumatology # ... Diagnosis #Management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Inflammatory Syndrome ... worsening of that disease ... cavitating pneumonia, skin ... -6 weeks after antifungal ... #Management
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... has five major clinical ... fungal stain of clinical ... for Coccidioides ... #Management #Infections
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