19 results
Ulcerative Blastomycosis Skin Lesion
57 asymptomatic M from Indiana nonpruritic, painless, progressive skin lesion lower back x
Diagnosis? ... Indiana University Infectious ... Diseases Fellowship ... #SkinRash #dermatology ... #clinical #photo
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
- Due to Viral infection ... Polyclonal - Viral Infection ... Check For: • Infections ... Polyclonal IgM post infectious ... #hematology #diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Mycoplasma pneumoniae infection ... spherocytosis) • Infections ... Extravascular #Causes #differential ... #diagnosis #hematology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
• Autoimmune diseases ... predictive of a serious infection ... overlook severe infections ... superior indicator of infection ... #WBC #CBC #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... arteritis Infections ... • Fungal infections ... Polyangiitis #GPA #dermatology ... #rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... weeks without infection ... Physical Exam/Signs ... cells can indicate disease ... workup #oncology #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... : HLH signs and ... can mimic common infections ... : • Infection ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... procedures - Infection ... practices that could ... not required in all ... #Workup #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
immunophenotype Clinical ... Complications: 1) Infection ... chemotherapy for low-risk disease ... lymphadenopathy and ... Leukemia #oncology #hematology
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
The signs and symptoms ... , the infection ... Syphilis #Rash #Diagnosis ... #Clinical #Photo ... #Dermatology