15 results
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Definition: An absolute eosinophil ... attributable to eosinophilia ... confirmed tissue eosinophilia ... with blood eosinophilia ... #eosinophils
Biologic therapy for eosinophilic asthma 
• Mepolizumab (Nucala) 
  • Anti-lL-5, 100 mg SQ q4
Biologic therapy for eosinophilic ... • Peripheral eosinophils ... • Peripheral eosinophils ... #pharmacology #pulmonary ... #management
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Syndrome #HES #Hematology ... #eosinophilia # ... eosinophils #diagnosis ... #management #algorithm
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Reaction with Eosinophilia ... lymphadenopathy, eosinophilia ... Eosinophilia 4 ... DRESS #Syndrome #dermatology ... #diagnosis #management
Eosinophilic Gastroenteritis: Treatment Options Based on Severity of the Disease
Mild:
 • Trial of PPI
 • Trial
Eosinophilic Gastroenteritis ... Concern for HES: • Hematology ... scan #EoE #Eosinophilic ... Gastroenteritis #Treatment #management
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Treatment
Stop offending agents:
 • List as allergies
Reaction with Eosinophilia ... Syndrome #Treatment #Management ... #dermatology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... polyangiitis), EGPA (eosinophilic ... Although pulmonary ... differential (check eosinophil ... differential #diagnosis #management
COPD Management Algorithm - GOLD 2019 guidelines 

Categorize into COPD GOLD A-D -> Initiate first-line therapy
COPD Management ... high levels of eosinophils ... who have high eosinophils ... GOLD2019 #Guidelines #Management ... #Pulmonary #Algorithm
Allergic Bronchopulmonary Aspergillosis (ABPA)
WHAT IS IT?
Hypersensitivity response to Aspergillus fumigatus in the airways
 • Primarily affects
• Peripheral eosinophilia ... Aspergillosis #ABPA #pulmonary ... #diagnosis #management
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
rarely present with eosinophilic ... solitary and multiple pulmonary ... pneumonia - Pulmonary ... Neutrophilia • Eosinophilia ... #diagnosis #management