Sgarbossa positive algorithm diagnosis differential diagram im pcc hepatology anemia disease agglutinin

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Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
1. Cold Agglutinins (CAD)
2. Donath-Landsteiner

• Symptoms of anemia ... anemia • Cold ... dehydrogenase • Positive ... younger pts) Differential ... #anemia #hematology

Hemolytic Anemia - Differential Diagnosis Algorithm
• Sickle cells - Consider sickle cell disease (diverse genotypes):

Hemolytic Anemia ... - Differential ... Diagnosis Algorithm ... Agglutination - Cold agglutinins ... Diagnosis #Algorithm

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