18 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... DIC/TTP/HUS - Hemolytic ... Diagnosis #hematology ... #nonpalpable #dermatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... thrombocytopenic purpura ... uremic syndrome ... Extravascular #Causes #differential ... #diagnosis #hematology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Palpable purpura ... Henoch Schönlein purpura ... Antiphospholipid-antibody syndrome ... Sarcoidosis #dermatology ... #rashes #differential
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... reticularis Differential ... • Goodpasture syndrome ... vasculitis #Dermatologic ... Polyangiitis #GPA #dermatology
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Leukocytoclastic Vasculitis Secondary ... Petechiae, Palpable purpura ... Vasculitis: • Behcet Disease ... • Cogan syndrome ... #dermatology #rheumatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Cholestatic liver disease ... Myelodisplastic syndrome ... Psychiatric Disease ... Pruritus #primary #secondary ... #generalized #dermatology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Approach to the differential ... glomerulonephritis; HUS = hemolytic-uremic ... syndrome; aHUS ... nose (epistaxis), skin ... loss, causing secondary
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
AIHA Primary Secondary ... lymphoproliferative disorder Secondary ... Cold Agglutinin Syndrome ... younger pts) Differential ... #hematology #diagnosis
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Vascular reactivity (Skin ... necrosis • Purpura ... Antiphospholipid syndrome ... Warfarin-induced skin ... #hematology
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
Diffuse and Focal) Differential ... • Loose anagen syndrome ... to Skin Disease ... HairLoss #Alopecia #dermatology ... #Differential #