13 results
causes algorithm oncology generalized pruritus rheumatology systemic alopecia arterial cold common cutaneous cvid embolism extravascular focal hairloss hemolysis hypogammaglobulinemia immunodeficiency
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... thrombocytopenic purpura ... . primary cold agglutin ... Extravascular #Causes #differential ... #diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Syndrome (CAS): ... Diagnosis: • hemolytic ... younger pts) Differential ... #disease #hemolytic ... #anemia #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... anemia - Splenomegaly ... Diagnosis #hematology ... #nonpalpable #dermatology
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Leukocytoclastic Vasculitis Secondary ... Petechiae, Palpable purpura ... Vasculitis: • Behcet Disease ... • Cogan syndrome ... #dermatology #rheumatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Diagnosis Algorithm ... renal failure/uremia ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #generalized #dermatology
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
and Focal) Differential ... Diagnosis Algorithm ... • Loose anagen syndrome ... to Skin Disease ... HairLoss #Alopecia #dermatology
Pustular Skin Lesions - Differential Diagnosis Framework What are pustules? • Pustules < 5-10 mm + pus • Material
- Differential ... Diagnosis Framework ... SAPHO syndrome ( ... Secondary syphilis ... #Diagnosis #Dermatology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... renal failure/uremia ... Myelodisplastic syndrome ... #Pruritus #secondary ... #generalized #dermatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... noninfectious complications ... and autoimmune hemolytic ... anemia) • Systemic ... hypogammaglobulinemia #immunology #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Coombs (-) hemolytic ... anemia due to cold ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
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