15 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... leakage of RBC's secondary ... DIC/TTP/HUS - Hemolytic ... Diagnosis #hematology ... #dermatology
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
with devastating differential ... vasculitic diseases secondary ... , the differential ... #Diagnosis #Dermatology ... #Nonpalpable #Differential
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Petechiae/Purpura ... Pathophysiology: ... of primary or secondary ... #Diagnosis #Dermatology ... #Differential #
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
thrombocytopenic purpura ... /hemolytic uremic ... syndrome. ... thrombocytopenia, Hematology ... #Diagnosis #Differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... thrombocytopenic purpura ... uremic syndrome ... Extravascular #Causes #differential ... #diagnosis #hematology
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Leukocytoclastic Vasculitis Secondary ... Vessel: Petechiae, Palpable ... purpura, Hemorrhagic ... Disease • Cogan syndrome ... Vasculitis #skin #dermatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Crohn's disease Palpable ... Henoch Schönlein purpura ... Antiphospholipid-antibody syndrome ... Sarcoidosis #dermatology ... #skin #rashes #differential
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
• Petechiae, Palpable ... • Petechiae • Palpable ... reticularis Differential ... • Goodpasture syndrome ... Polyangiitis #GPA #dermatology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Diagnosis Secondary ... iron deficiency, hemolysis ... Myelodysplastic syndrome ... Diagnosis #Causes #hematology ... #secondary
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... in primary or secondary ... Henoch Schonlein Purpura ... Rash: - Purpura ... Algorithm #Causes #dermatology