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diagnosis dermatology differential oncology alopecia focal generalized hairloss pruritus systemic anemia aplastic atlas basics diffuse disorders eosinophil key lesions leukemia
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Testing Algorithm ... • Screen for secondary ... causes of eosinophilia ... symptoms (eg, skin ... Differential #diagnosis #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Abnormalities in primary ... or secondary hemostasis ... cryoglobulins • Skin ... #Causes #dermatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis Algorithm ... Causes == Primary ... #secondary #systemic ... #generalized #dermatology ... #causes
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Differential Diagnosis Algorithm ... decalvans - Secondary ... to Skin Disease ... Congenital hair shaft ... #causes
Primary Dermatological Lesions Primary lesions are physical changes in the skin considered to be caused directly by
considered to be caused ... associated with secondary ... PETECHIAE and PURPURA ... : Petechiae are ... #Skin #Primary
Focal / Localized Hair Loss (Alopecia) - Differential Diagnosis Algorithm Scarring - Irreversible-biopsy required - Infectious
Differential Diagnosis Algorithm ... decalvans - Secondary ... to Skin Disease ... Congenital hair shaft ... #causes
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... Skin Lesion - Differential ... Diagnosis Algorithm ... #Pruritus #secondary ... #causes
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
• (Peripheral eosinophilia ... + distinctive primary ... bone marrow and secondary ... CLL -> Invade Skin ... #Leukemia #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... bleeding, and petechiae ... Causes: • Constitutional ... - Hepatitis, eosinophilic ... #diagnosis #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... other diseases • Secondary ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... #Diagnosis #Management
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