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diagnosis differential vasculitis classification dermatology oncology alopecia antiphospholipid apls behcets chronic cll cryofibrinogenemia cryoglobulinemia cryoglobulins diffuse disease disorders eosinophil eosinophilia
Genital Skin Ulcers - Differential Diagnosis Algorithm Painful: • Herpes simplex • Haemophilus ducreyi (chancroid) • Behcet's
Genital Skin Ulcers ... Differential Diagnosis Algorithm ... ) • Behcet's syndrome ... ulcerative #skinrash #dermatology ... #causes
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... evaluation or workup ... 1,500 cells/µL Workup ... symptoms (eg, skin ... Differential #diagnosis #hematology
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... - Treatment Ulcers ... refractory disease Skin ... Behcets #disease #Syndrome ... #pharmacology #rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
sensitivity • Painful ulcers ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... ulcers - Glomerulonephritis ... Cryoglobulins Cause ... classification #rheumatology
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Differential Diagnosis Algorithm ... • Loose anagen syndrome ... - Secondary to Skin ... Congenital hair shaft ... #causes
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... plaques, nodules, ulcers ... • Richter’s Syndrome ... Leukemia #diagnosis #workup ... #oncology #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... livedo reticularis, ulcers ... genital aphthous ulcers ... • Cogan Syndrome ... differential #diagnosis #rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... just beneath the skin ... characteristic feature ... Workup: • Complete ... #diagnosis #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
livedo reticularis, ulcers ... tract, and often causes ... purpura, nodules or ulcers ... genital aphthous ulcers ... Differential #Diagnosis #Rheumatology
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