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diagnosis differential symptoms oncology vasculitis arthritis behcet chronic classification cll disease disorders eosinophil eosinophilia leukemia lymphocytic management mds myelodysplasia myelodysplastic
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
thickening Signs ... Raynaud's, digital ulcers ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... symptoms #testing #workup
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... evaluation or workup ... organ-specific signs ... symptoms (eg, skin ... Differential #diagnosis #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
response to local skin ... recurrent oral ulcers ... test (this is a skin ... diagnosis #management #signs ... #symptoms #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Hepatomegaly • Skin ... plaques, nodules, ulcers ... Leukemia #diagnosis #workup ... #oncology #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
livedo reticularis, ulcers ... genital aphthous ulcers ... • Cogan Syndrome ... purpura: strong sign ... differential #diagnosis #rheumatology
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Rheumatoid Arthritis - Signs ... Complications of DMARDs • Skin ... gastritis and peptic ulcer ... Thrombocytosis, Felty's syndrome ... Symptoms #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... livedo reticularis, ulcers ... purpura, nodules or ulcers ... genital aphthous ulcers ... Differential #Diagnosis #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... just beneath the skin ... characteristic feature ... Workup: • Complete ... #diagnosis #hematology
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