17 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... hydration - Hyperkalemia ... unless worrisome EKG
Emergent Hyperkalemia Treatment Algorithm
ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia ... Treatment Algorithm ... cardiac membrane Shift ... not to be used as ... #Treatment #Algorithm
Evaluation and Management of Hypokalemia

Hypokalemia is often asymptomatic. Evaluation begins with a search for warning signs
search for warning signs ... or symptoms warranting ... electrocardiography (ECG ... transcellular shifts ... hypomagnesemia are also
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
wasting crisis & hyperkalemia ... • This is also ... Signs/Symptoms/Complications ... : • Hyperkalemia ... #21HydroxylaseDeficiency #21OHD #pathophysiology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
: • Triad of symptoms ... urine • Other symptoms ... HAGMA • Late complication ... Shift of extracellular ... Treatment of underlying
Medications for the Treatment of Hyperkalemia
The goals of acute treatment are to prevent potentially life-threatening cardiac
disturbances, shift ... intervention are symptoms ... , changes on ECG ... Figure 3 is an algorithm ... #Treatment
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
When present, symptoms ... , signs, and complications ... • "Vasomotor" symptoms ... : • As with ET ... • Treatment algorithms
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... neoplasms) • Screen also ... glucocorticoid treatment ... organ-specific signs ... or symptoms (eg
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
adenomas that require treatment ... non-secreting (30%) as ... Signs / Symptoms ... / Complications ... mnemonic #GLFTAP #pathophysiology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
To prevent hypokalemia ... with IV insulin as ... soon as serum < ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology