17 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... hydration - Hyperkalemia ... unless worrisome EKG ... #TLS #diagnosis
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
HIV, Influenza, TSS ... Dermatomyositis Clinical ... • LDH ↑ • Hyperkalemia ... Shift of extracellular ... Dialysis for severe hyperkalemia
Evaluation and Management of Hypokalemia

Hypokalemia is often asymptomatic. Evaluation begins with a search for warning signs
Hypokalemia is ... search for warning signs ... or symptoms warranting ... electrocardiography (ECG ... transcellular shifts
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
iniury, Compartment syndrome ... HIV, Influenza, TSS ... Dermatomyositis) AKI - Pathophysiology ... Shift of extracellular ... Dialysis for severe hyperkalemia
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Pathogenesis and Clinical ... wasting crisis & hyperkalemia ... Signs/Symptoms/Complications ... : • Hyperkalemia ... #21HydroxylaseDeficiency #21OHD #pathophysiology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
hypertension and signs ... disorders including hypokalemia ... 109 mm Hg) with clinical ... renal bruit or signs ... Hyperthyroidism, Hypercalcemia
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Refeeding Syndrome ... Pathogenesis and clinical ... Metabolic Acidosis • Shift ... #diagnosis #pathophysiology ... #symptoms #signs
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of the clinical ... lateral sclerosis Pathophysiology ... cellular function Clinical ... fasciculations Common Symptoms ... EMG: LMN Signs in
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Pathogenesis and Clinical ... To prevent hypokalemia ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology
Clinical Feature of Hypomagnesemia and Magnesium Deficiency
 • Electrolyte Disturbance: Hypokalemia, Hypocalcemia
 • Neuromuscular and central
Clinical Feature ... Electrolyte Disturbance: Hypokalemia ... Chronic fatigue syndrome ... Hypomagnesemia #diagnosis #signs ... #symptoms #Treatment