8 results
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
action on the nephron ... (e.g. ... triamterene) #nephron ... #diuretics #pharmacology ... #nephrology #medications
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... ) Loop agents (eg ... Adenosine #Nephron ... Sites #Action #nephrology ... #pharmacology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Diagnosis Algorithm ... Transcellular Shift ... • Discontinued diuretic ... #nephrology #low
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm
Transcellular Shift - Appropriate renal excretion (GFR,
Causes of Hyperkalemia ... Intercellular Shift ... • Cell Lysis (e.g ... #IntercellularShift ... #Nephrology #Differential
Hypokalemia Differential Algorithm
Acidosis
 - RTA
 - Diarrhea
pH Normal 
 1. Decreased Mg 
 2. Intracellular Shift
Hypokalemia Differential ... Algorithm Acidosis ... Intracellular Shift ... Diuretics (discontinued ... Causes #Workup #Nephrology
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm

Reduced flow through distal nephron - TTKG
Causes of Hyperkalemia ... through distal nephron ... • Low EABV (e.g ... #IntercellularShift ... #Nephrology #Differential
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
Algorithm for patients ... with hypokalemia ... creatinine) • Cell shift ... , Thiazide diuretics ... #diagnosis #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Decreased intake (rare cause in isolation)
GI loss - Urine loss
Causes of Hypokalemia ... Differential Diagnosis Algorithm ... Transcellular shift ... #Nephrology #Differential ... #Diagnosis #Algorithm