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diagnosis management algorithm causes differential neurology 21hydroxylasedeficiency 21ohd amyotrophic encephalopathy evaluation genetics hyperthyroidism hypokalemia lateral pathophysiology peds posterior pres reversible
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
wasting crisis & hyperkalemia ... Signs/Symptoms/Complications ... : • Hyperkalemia ... pathophysiology #genetics #endocrinology ... #peds #pediatrics
Emergent Hyperkalemia Treatment Algorithm ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia ... cardiac membrane Shift ... not to be used as ... kayexelate) and others lower ... not quickly) #Hyperkalemia
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
5X ULN • AST/ALT ... • LDH ↑ • Hyperkalemia ... Shift of extracellular ... Treatment of underlying ... #nephrology
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
↑ T3 - Mild hypercalcemia ... • Treatment: ... tenderness Treatment ... #differential #endocrinology ... #signs #symptoms
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of UMN and LMN signs ... Upper extremity, lower ... EMG: LMN Signs in ... diagnosis column Treatment ... Lateral #Sclerosis #neurology
Evaluation and Management of Hypokalemia Hypokalemia is often asymptomatic. Evaluation begins with a search for warning signs
search for warning signs ... warranting urgent treatment ... transcellular shifts ... Identification and treatment ... hypomagnesemia are also
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 Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Blood transfusion, Hypercalcemia ... edema visualized as ... epilepticus Treatment ... underlying cause • Treatment ... BP lowering - Lower
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