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management diagnosis algorithm nephrology potassium causes differential high rhabdomyolysis syndrome 21hydroxylasedeficiency chvostek clinical genetics gitelman hematology hypocalcemia leukostasis lysis pediatrics
Emergency Management of Hyperkalemia in Adults Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach •
Management of Hyperkalemia ... the Heart • Calcium ... Chloride OR Calcium ... Gluconate IV Shift ... recurrence #Hyperkalemia
Hyperkalemia Treatment Options Stabilize cardiac membrane: • IV Calcium (peaks 5-10 minutes) Decrease potassium concentration: • IV Fluids Shift
Hyperkalemia Treatment ... membrane: • IV Calcium ... • IV Fluids Shift ... LouLectures #Hyperkalemia
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
wasting crisis & hyperkalemia ... Complications: • Hyperkalemia ... #21HydroxylaseDeficiency #21OHD ... #pathophysiology ... #genetics #endocrinology
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
Hyperkalemia - Management ... Algorithm • IV calcium ... blocks, QRS axis shift ... , asystole #hyperkalemia ... management #algorithm #treatment
Emergent Hyperkalemia Treatment Algorithm ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia ... Treatment Algorithm ... AV blocks) -> Calcium ... cardiac membrane Shift ... not quickly) #Hyperkalemia
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
• LDH ↑ • Hyperkalemia ... /Late - Hypercalcemia ... Shift of extracellular ... potassium and calcium ... Dialysis for severe hyperkalemia
The Chvostek sign (/ˈkvɒstɪk/) is a clinical sign of existing nerve hyperexcitability (tetany) seen in hypocalcemia.It
lips) because of hypocalcemia ... with a normal calcium ... level due to a shift ... #PhysicalExam # ... Video #Clinical #endocrinology
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 Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Lysis Syndrome: • Pathophysiology ... • Treatment: ... hydration - Hyperkalemia ... treatment (no calcium
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Dermatomyositis) AKI - Pathophysiology ... Shift of extracellular ... oxidative iniury Treatment ... potassium and calcium ... Dialysis for severe hyperkalemia
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Family history of hypokalemia ... • Unexplained hypokalemia ... pressure Labs: • Hypokalemia ... Rhabdomyolysis Treatment ... #Hypokalemia
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