29 results
IBS-C Pharmacotherapy

Polyethylene glycol
Lubiprostone
Linaclotide
Plecanatide
Tegaserod
Tenapanor

#IBSC #IBS #Constipation #Irritable #Bowel #Syndrome #pharmacology #table #comparison #management #treatment
Irritable #Bowel #Syndrome ... #pharmacology # ... table #comparison ... #management #treatment
IBS-D Pharmacotherapy

Loperamide
Rifaximin
Eluxadoline
Alosetron
Antispasmodics
Tricyclic antidepressants
SSRIs

#IBSD #IBS #Diarrhea #Irritable #Bowel #Syndrome #pharmacology #table #comparison #management #treatment
Irritable #Bowel #Syndrome ... #pharmacology # ... table #comparison ... #management #treatment
Emergency Management of Hyperkalemia in Adults
Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach
 •
Management of Hyperkalemia ... mmol/L - Consider cause ... clinical scenario, ECG ... Gluconate IV Shift ... Prevention - Consider cause
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
polyneuropathy (e.g ... Guillain-Barré syndrome ... Hyperreflexia: • Hypocalcemia ... Hyperthyroidism, Serotonin syndrome ... differential #diagnosis #table
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... Transcellular Shifts ... plasma insulin (treatment ... use), Gitelman's syndrome ... #Causes #differential
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... constipation, diarrhea, nausea ... ); nausea, vomiting ... #medications #pharmacology ... #table #comparison
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... - Compartment syndrome ... Shift of extracellular ... per day until stable ... Diagnosis #Management #causes
Vasopressors Table 
Rough properties by Target Receptor, Heart Rate/Inotropy, Systemic Vascular Resistance, Cardiac Output, Blood Pressure,
Vasopressors Table ... Resistance, Main Uses ... Vasopressors #Properties #Table ... #Pharmacology # ... Effect #Management #Comparison
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Shift of extracellular ... per day until stable ... Dialysis for severe hyperkalemia ... Management #Summary #causes ... #treatment
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Management of Hyperkalemia ... Binders #Management #Hyperkalemia ... #treatment #pharmacology ... #table #comparison