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management diagnosis differential causes foamed nephrology pharmacology tls adrenalmass cardiology chf crystalloids endocrinology evaluation heartfailure high intercellularshift lysis malignant medications
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
of Tumor Lysis Syndrome ... Calcium ≤ 7.0 mg/dL Clinical ... hydroxide • Hyperkalemia ... #TumorLysis #Syndrome ... diagnosis #management #oncology
Emergency Management of Hyperkalemia in Adults Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach •
Management of Hyperkalemia ... guided by clinical ... scenario, ECG and ... Gluconate IV Shift ... recurrence #Hyperkalemia
Medications for the Treatment of Hyperkalemia The goals of acute treatment are to prevent potentially life-threatening cardiac
of Hyperkalemia ... disturbances, shift ... , changes on ECG ... , severe hyperkalemia ... Figure 3 is an algorithm
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 Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
Hyperkalemia - Management ... potassium and ECG ... blocks, QRS axis shift ... , asystole #hyperkalemia ... #treatment
Emergent Hyperkalemia Treatment Algorithm ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia ... Treatment Algorithm ... cardiac membrane Shift ... not quickly) #Hyperkalemia ... #Treatment #Algorithm
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... 6L/day) • For hyperkalemia ... with Ca only if EKG ... otherwise treat with "hyperkalemia ... #TLS #oncology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Compartment syndrome ... Dermatomyositis Clinical ... • LDH ↑ • Hyperkalemia ... Shift of extracellular ... Dialysis for severe hyperkalemia
Evaluation and Management of Hypokalemia Hypokalemia is often asymptomatic. Evaluation begins with a search for warning signs
Management of Hypokalemia ... Hypokalemia is ... electrocardiography (ECG ... transcellular shifts ... #Evaluation #Algorithm
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 Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm Transcellular Shift - Appropriate renal excretion (GFR,
Causes of Hyperkalemia ... Intercellular Shift ... • Cell Lysis (e.g ... Tumor Lysis Syndrome ... • Digoxin #Hyperkalemia
Recurrent Polymorphic VT/Torsades de Pointes - Management Algorithm Drugs that prolong QT interval: • Class 1a (quinidine,
Pointes - Management Algorithm ... Congenital long QT Syndrome ... Hypomagnesemia • Hypokalemia ... • Hypocalcemia ... (rarely) Treatment
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