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diagnosis differential nephrology causes hyperkalemia high comparison crrt druginduced effects gitelman lactated lr managment medications modalities modes ncpe noncardiogenic normal
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC shift ... Benyzlpenicillin, blood ... differential #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Clenching of fist during ... Crush injury • Blood ... transfusion • HTN and edema ... Intracellular Shift ... Blood transfusion
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Clenching of fist during ... Crush injury • Blood ... transfusion • HTN and edema ... Intracellular Shift ... Blood transfusion
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison Composition of LR: • Sodium 130 mEq/L •
130 mEq/L • Potassium ... Can give with blood ... Is Dangerous in Hyperkalemia ... transcellular shift ... NS #comparison #pharmacology
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework High Altitude Pulmonary Edema: • Accumulation
: The shift of fluid ... shortly after or during ... , hypotension, hypovolemia ... : • Pathophysiology ... pleural fluid by rising
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
salt-losing tubulopathies ... Normal or low blood ... (renal potassium ... diagnosis #nephrology #management ... #pathophysiology
Renal Replacement Therapy (RRT) - ICU One Pager Summary Indications (AIEOU): • A: Acidosis (usually severe metabolic)
derangements (hyperkalemia ... Overload (pulmonary edema ... • Blood Flow ... dialysate flow (both convection ... #Therapy #RRT #managment
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