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hyperkalemia management diagnosis differential algorithm causes comparison pharmacology binding medications agents effects gitelman k kayexelate kbinders kdigo lactated lr normal
Key Characteristics of Old and New Potassium-Binding Agents - Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd #Potassium #Binding #KBinders #Kayexelate
edgarvlermamd #Potassium ... #Binding #KBinders ... Kayexelate #Comparison #Table ... Pharmacology #Patiromer #HyperKalemia ... #Nephrology #Agents
Potassium Binders for Management of Hyperkalemia • SPS - Sodium polystyrene sulfonate • Patiromer (veltassa) •
Potassium Binders ... #Hyperkalemia # ... treatment #pharmacology ... #table #comparison ... #nephrology
Hyperkalemia Treatment Options Stabilize cardiac membrane: • IV Calcium (peaks 5-10 minutes) Decrease potassium concentration: • IV Fluids Shift
Hyperkalemia Treatment ... minutes) Decrease potassium ... • IV Fluids Shift ... LouLectures #Hyperkalemia ... #nephrology
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... nonspecifically binds ... patients sensitive to high ... of aspiration #Potassium ... #pharmacology #table
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine Urine K+
patients with hypokalemia ... the basis of the potassium-to-creatinine ... creatinine) • Cell shift ... #urine #potassium ... algorithm #diagnosis #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Shift of extracellular ... fluid/Lactated ringers ... Monitor potassium ... per day until stable ... #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
phlebotomy High ... • Recent IV potassium ... Intracellular Shift ... lysis syndrome - Rhabdomyolysis ... #high #nephrology
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
Hyperkalemia - Management ... • Consider K+ binder ... blocks, QRS axis shift ... #potassium #high ... management #algorithm #treatment
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
phlebotomy High ... • Recent IV potassium ... Intracellular Shift ... lysis syndrome - Rhabdomyolysis ... #high #nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Shift of extracellular ... oxidative iniury Treatment ... Monitor potassium ... per day until stable ... Dialysis for severe hyperkalemia
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