11 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
Agents - Dr. ... edgarvlermamd #Potassium ... #Binding #KBinders ... Pharmacology #Patiromer #HyperKalemia ... #Nephrology #Agents
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... #Binders #Management ... #Hyperkalemia # ... treatment #pharmacology ... table #comparison #nephrology
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
) MECHANISM: Potassium ... Binder INDICATION ... : Treatment of Hyperkalemia ... binder that can ... #Binder #KBinder
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... Agents to Treat ... nonspecifically binds ... of aspiration #Potassium ... table #comparison #binders
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
Hyperkalemia Treatment ... minutes) Decrease potassium ... • IV Fluids Shift ... LouLectures #Hyperkalemia ... #nephrology
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... • Consider K+ binder ... blocks, QRS axis shift ... #potassium #high ... management #algorithm #treatment
KDIGO Treatment algorithm for management of acute hyperkalemia in the emergency department
 • Place on cardiac
KDIGO Treatment ... management of acute hyperkalemia ... • Consider K+ binder ... #potassium #high ... #nephrology #KDIGO
Algorithm for Management of Acute and Chronic Hyperkalemia
Acute Hyperkalemia:
 - IV calcium (10 mL of 10%)
Acute Hyperkalemia ... - Consider K+ binders ... bicarbonate - Consider binders ... Acute #Chronic #treatment ... #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Shift of extracellular ... Treatment of underlying ... fluid/Lactated ringers ... Monitor potassium ... #nephrology
Emergent Hyperkalemia Treatment Algorithm
ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia ... cardiac membrane Shift ... Remove potassium ... removal of offending agent ... not quickly) #Hyperkalemia