25 results
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... Agents Subclass, Drug ... Chlorthalidone POTASSIUM-SPARING ... #Medications #Pharmacology ... summary #table #nephrology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Transcellular Shift ... Thyrotoxicosis Medications ... • Discontinued diuretic ... Diagnosis #Algorithm #nephrology ... #low #potassium
Antiarrhythmic Drugs

CLASS IA
 • Procainamide, Quinidine, Disopyramide
CLASS 1B
 • Lidocaine, Mexiletine
CLASS 2
 • Propranolol, Esmolol
CLASS 4
Antiarrhythmic Drugs ... Adenosine, Magnesium, Potassium ... Antiarrhythmic #Medications ... #Classes #Classification ... #Pharmacology #
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
Drugs associated ... Hypokalemia - Shift ... hypomagnesemia #Medications ... differential #diagnosis #nephrology ... #Causes #hypomg
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
sodium, which causes ... classes (Aliskiren ... , ACEI, ARB, and ... diuretic, which ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology
ACEI or ARB Initiation
Hyperkalemia:
 - Review concurrent drugs
 - Moderate potassium Intake
 - Consider: diuretics, sodium
ACEI or ARB Initiation ... Review concurrent drugs ... - Moderate potassium ... - Review for causes ... Reassess concomitant medications
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... Angiotensin-converting enzyme (ACE ... • Increased EC shift ... pathophysiology #pharmacology ... #potassium #medications
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
Causes of Hypomagnesemia ... - Potassium depletion ... Hypomagnesemia #Causes ... #differential #medications ... #drugs #pharmacology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• NSAIDs • ACE ... Intracellular Shift ... Medications 2. ... differential #diagnosis #causes ... #nephrology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... Transcellular Shifts ... Conn's, Liddle's), Drugs ... #Hypokalemia #Causes ... differential #diagnosis #nephrology