18 results
Causes of Hyperkalemia - Differential Diagnosis Algorithm
 • Increased Intake
 • Reduced Excretion (IV potassium with
Causes of Hyperkalemia ... Excretion (IV potassium ... Transcellular Shift ... #Hyperkalemia ... #Nephrology #Differential
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
edgarvlermamd #Potassium ... Kayexelate #Comparison #Table ... #Pharmacology # ... Patiromer #HyperKalemia ... #Nephrology #Agents
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
Hyperkalemia Treatment ... minutes) Decrease potassium ... • IV Fluids Shift ... LouLectures #Hyperkalemia ... #nephrology
Causes of Hypokalemia

Hypokalemia results from abnormal losses, transcellular shifts, or insufficient intake (Table 1).6–8 Abnormal losses
Causes of Hypokalemia ... transcellular shifts ... insufficient intake (Table ... significantly lower potassium ... rarely the sole cause
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... Management of Hyperkalemia ... #treatment #pharmacology ... #table #comparison ... #nephrology
Hyperkalemia Management Algorithm
 • Treat the cause & optimize hemodynamics and ventilation
 • Reconsider treatment leadingto
• Treat the cause ... • Reconsider treatment ... and parenteral potassium ... Intracellular K+ Shift ... #potassium #high
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... ); nausea, vomiting ... of aspiration #Potassium ... #medications #pharmacology ... #table #comparison
Medications for the Treatment of Hyperkalemia
The goals of acute treatment are to prevent potentially life-threatening cardiac
Medications for the Treatment ... goals of acute treatment ... disturbances, shift ... , and Table 3 summarizes ... #Treatment
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• Recent IV potassium ... Intracellular Shift ... differential #diagnosis #causes ... #potassium #high ... #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... Shift of extracellular ... Monitor potassium ... per day until stable ... #treatment #nephrology