26 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Hemoglobinuria (PCH ... Test: Donath-Landsteiner ... test #cold # ... agglutinin #disease ... hemolytic #anemia #hematology
Diagnostic Schema for Hyperferritinemia

Pearl: Diseases associated with extreme elevations: 
1. HLH 
2. Still's disease 
3. Systemic
Diagnostic Schema ... Still's disease ... Systemic histoplasmosis ... Hyperferritinemia #Algorithm ... #Hematology
Expected DAT Results in Autoimmune Hemolysis
DAT Negative Hemolysis
 • DAT Poly ( - ), IgG (
( +/- ) Cold agglutinin ... disease • DAT ... #antiglobulin #test ... Autoimmune #Hemolysis #hematology ... #diagnosis
Mucous Membrane Disorder - Differential Diagnosis Algorithm
Erosions/Ulcers/Blisters
 - Primary Dermatologic Diseases
     •
- Differential Diagnosis ... Algorithm Erosions ... Systemic lupus ... MucousMembranes #dermatology ... #Algorithm #causes
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Generalized Differential Diagnosis ... Algorithm - Systemic ... Liver Function Tests ... #generalized #dermatology ... #Algorithm #causes
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
- Differential Diagnosis ... Algorithm Infectious ... Inflammatory • Systemic ... #Algorithm #Causes ... #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Algorithm • Sickle ... Agglutination - Cold agglutinins ... #Algorithm #workup ... #hematology #testing
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
- Differential Diagnosis ... Algorithm Thrombocytopenia ... Vascular System ... #Algorithm #Causes ... #Hematology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Diseases Nail ... disease severe ... #Secondary #dermatology ... #Differential #Diagnosis ... #Algorithm #causes
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm

Elevated Hemoglobin:
 • Males: Hb > 16.5 g/dL/HCT ≥ 49%
 •
Polycythemia Differential Diagnosis ... Algorithm Elevated ... Cardiac/pulmonary disease ... #Differential #Diagnosis ... #Algorithm #hematology