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differential causes workup secondary generalized hemolytic oncology pruritus activation central chronic cll cold elevatedmcv hemolysis leukemia lymphocytic macrocytic macrocytosis macrophage
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
anemia • Cold ... Test: Donath-Landsteiner ... test #cold # ... agglutinin #disease ... #hematology #diagnosis
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Diseases Nail ... Iron deficiency anemia ... #Secondary #dermatology ... #Differential #Diagnosis ... #Algorithm #causes
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... Algorithm • Sickle ... Agglutination - Cold agglutinins ... #hematology #testing
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Generalized Differential Diagnosis ... Algorithm - Systemic ... Liver Function Tests ... renal failure/uremia ... #generalized #dermatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Algorithm Normal ... Liver Function Tests ... #Algorithm #Causes ... #Hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... Drug-associated, PCH ... Defects: Sickle cell anemia ... Laboratory Tests ... #hematology
Maculopapular Rashes - THE ALGORITHMIC APPROACH The term maculopapule is a portmanteau, a combination of macule and
Maculopapular Rashes - THE ALGORITHMIC ... assessed for Lyme disease ... pathognomonic for SJS or EM ... #Diagnosis #Dermatology ... Maculopapular #Rash #Algorithm
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Algorithm Blood ... Liver Function Tests ... renal failure/uremia ... Pruritus #secondary #systemic ... #generalized #dermatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... value is low, tests ... result in severe anemia ... leukocytosis with a left shift ... #Workup #Hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... WAIHA • CAD • PCH ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Differential #Diagnosis
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