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diagnosis hematology arthritis cold deficiency differential evaluation gastroenterology gastrointestinal laboratory mds myelodysplasia myelodysplastic oncology rheumatic rheumatoid rheumatology syndromes
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
AIHA Primary Secondary ... Positive Coombs testing ... • Diagnostic Test ... Donath-Landsteiner test ... #disease #hemolytic
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... Agglutination - Cold agglutinins ... #workup #hematology ... #testing
Gastrointestinal Evaluation of Iron Deficiency Anemia In patients with anemia, diagnose iron deficiency if: • Ferritin <
inflammation or chronic ... kidney tests Test ... for celiac disease ... Non-invasive testing ... Gastrointestinal #Evaluation #workup
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... for Chronic Polyarthritis ... ferritin level, and iron ... Arthritis #laboratory #workup
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... DDX: Rule Out Secondary ... Marrow Failure • Chronic ... Myeloproliferative Disease ... rings of excess iron
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