31 results
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... - Differential Diagnosis ... #Effusions #causes ... #differential #diagnosis ... #msk #physicalexam
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... Neoplastic / Hematologic ... Autoimmune / Inflammatory ... Obstructive Pulmonary Disease ... Chronic Fatigue Syndrome
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
be any age) Autoimmune ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK ... Diagnosis #Management
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
and Management ... in the US: Autoimmune ... fungal infection, HIV ... hypophysitis, Sheehan's syndrome ... A STIM test can
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Non-inflammatory Causes ... and less common diseases ... an underlying autoimmune ... pachymeningitis • HIV ... consistent with MS
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral infection, autoimmune ... Mycoplasma, EBV, HIV ... test #cold # ... hemolytic #anemia #hematology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
- Differential Diagnosis ... and Management ... Hyperthyroidism), Autoimme ... Shift of extracellular ... #causes #treatment
Bone Deformity / Limp - Differential Diagnosis Algorithm 
Infection
 • Septic Arthritis
 • Cortical Hypertrophy
 •
- Differential Diagnosis ... Arthritis Other Causes ... Knee Joint • ... Patellofemoral Syndrome ... Deformity #Limp #MSK
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Summary Causes ... Hyperthyroidism - Autoimmune ... Shift of extracellular ... of underlying disease ... #Management #causes