17 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Etiology: • Vascular ... - Hemolytic anemia ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Quinidine • HIT ... Non-lmmune: • HELLP Syndrome ... HUS • DIC • Vasculitis ... #Hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Pruritus - Generalized ... Differential Diagnosis ... Liver Function Tests ... renal failure/uremia ... Myelodisplastic syndrome
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... - Differential Diagnosis ... #Effusions #causes ... #differential #diagnosis ... #msk #physicalexam
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... - HCV - HIV ... #oncology #hematology ... #diagnosis #management
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Etiology - Mixed ... HBV infection, HIV ... Labs/Diagnosis:
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... - Differential Diagnosis ... Petechiae Etiology ... ITP - APLS - HIT ... Fecal occult blood test
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Pruritus - No Primary ... Liver Function Tests ... renal failure/uremia ... Myelodisplastic syndrome ... #Algorithm #causes
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... tract, and often causes ... retinopathy Lab Tests ... Cryoglobulins • HIV ... #rheumatology #
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Cold Agglutinin Syndrome ... Mycoplasma, EBV, HIV ... test #cold # ... #hematology #diagnosis