11 results
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... - Differential Diagnosis ... #Effusions #causes ... #differential #diagnosis ... #msk #physicalexam
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... : • Clinical triad ... HBV infection, HIV ... Labs/Diagnosis:
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... tract, and often causes ... retinopathy Lab Tests ... Cryoglobulins • HIV ... #rheumatology #
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
Pathogenesis and Clinical ... nephrotic/nephritic syndrome ... arthritis (especially knees ... and ankles) #HSP ... Pathophysiology #Diagnosis
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... ) • Cutaneous vasculitis ... : 2% Systemic Vasculitis ... phenomenon (16%) MSK
Hearing Loss - Differential Diagnosis Framework

Hearing Loss Types:
• Conductive
• Sensorineural
• Mixed
Presbycusis is the most common type
- Differential Diagnosis ... • Stroke • Vasculitis ... cause unknown) ... II ○ Susac’s syndrome ... Noise trauma ○ MS
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Bleeding and Bruising ... von Willebrand syndrome ... discern these causes ... integrity == • Vasculitis ... #Hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Cold Agglutinin Syndrome ... Viral Infection Clinical ... test #cold # ... hemolytic #anemia #hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
malignancies, vasculitis ... : • + Clinical ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... hematology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... bouts of HTN Diagnostic ... Transverse Myelitis Diagnosis ... negative, MOG-IgG test ... - Sjogren - Vasculitis