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differential hepatology liver rheumatology algorithm workup vasculitis arthritis autoimmune biliary bronchiectasis causes chemistry cholangitis chronic cirrhosis classification cll enzymes hellp
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... necrosis HELLP Syndrome ... #obstetrics #hepatitis ... #comparison #differential ... #diagnosis #icp
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Pregnancy - AFLP ... • Cholestatic disease ... US — Normal Bile ... • Alcoholic hepatitis ... • Others #LFTs
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... of cholestatic disease ... • Gilbert's syndrome ... liver #chemistry #diagnosis ... transaminitis #LFTs
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
clinical symptoms/signs ... presence of metabolic syndrome ... ALP, alkaline phosphatase ... #LFTs #Abnormal ... #Algorithm #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... vein: Budd-chiari syndrome ... source - Tests ... function may be abnormal ... • Gilbert's syndrome
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
IgM) levels • Hepatitis ... (LFTs) and a serum ... (to support a diagnosis ... arthritis) • Hepatitis ... laboratory #workup #diagnosis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
failure PBC Signs ... but elevated as disease ... obstruction • ALP ... : • Viral hepatitis ... #workup #hepatology
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
Connective tissue diseases ... • Mounier-Kuhn syndrome ... Nasal polyps and signs ... parenchyma Diagnosis ... - BAR >1.0 is abnormal
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... purpura: strong sign ... retinopathy Lab Tests ... : • CBC • LFT ... #rheumatology #
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
adults in the west ... Physical Exam/Signs ... cells can indicate disease ... cell aplasia • ITP ... workup #oncology #hematology
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