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differential hepatology liver algorithm rheumatology vasculitis autoimmune causes chemistry classification disease hellp injury interpretation liverenzymes myopathy myositis obstetrics pregnancy rvalue
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Pregnancy - AFLP ... disease US — Normal ... • Alcoholic hepatitis ... • Others #LFTs
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
necrosis HELLP Syndrome ... Elevated Liver enzymes ... #obstetrics #hepatitis ... #comparison #differential ... #diagnosis #icp
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
clinical symptoms/signs ... presence of metabolic syndrome ... the magnitude of enzyme ... #LFTs #Abnormal ... #Liver #Enzymes
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... Source of Liver Enzyme ... • Gilbert's syndrome ... liver #chemistry #diagnosis ... transaminitis #LFTs
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... vein: Budd-chiari syndrome ... source - Tests ... • Gilbert's syndrome ... Source of Liver Enzyme
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... purpura: strong sign ... retinopathy Lab Tests ... : • CBC • LFT ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... purpura: Strong sign ... Muscle strength & enzymes ... fluid (CSF) is abnormal ... #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Tests: • Measure ... papules and Gottron sign ... ) • Shawl sign ... Anti-aminoacyl-tRNA synthetase enzymes ... PBC, autoimmune hepatitis
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