36 results
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... thrombophlebitis Skin ... band syndrome • Shin ... Brittle nails - Skin ... skin • Inflammation
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
and signs. ... malaise, Weight gain ... , Dry coarse skin ... Goitre), Dry skin ... #PhysicalExam #
Clinical manifestations of anaphylaxis. 
Neurological (<15%): Dizziness, syncope, seizures, Confusion, impending doom. headache
Angioedema: Lips, tongue, orbit,
intestines, extremities Skin ... (Skin and Mucosa ... edema, abdominal pain ... #anaphylaxis #signs ... #symptoms #diagnosis
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
rubbing of the skin ... Staphylococcal scalded skin ... syndrome, caused ... #Video #Clinical ... #SJS #skin
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
aldosterone Causes ... : Most Common Causes ... • Abdominal pain ... • Back pain ... patches on the skin
Pathyophysiology - hyperglycemic crises in patients with diabetes 
Key signs/symptoms of HHS/DKA:
Both: Polyuria, polydipsia, weight loss,
hyperglycemic crises ... diabetes Key signs ... /symptoms of HHS ... hypovolemia (dry MM, skin ... diffuse abdominal pain
CLINICAL MANIFESTATIONS 
OF ADRENAL INSUFFICIENCY. 

Primary and secondary adrenal insufficiency:
 - Tiredness, weakness, mental depression
Primary and secondary ... hypotension - Nausea ... eosinophilia Primary ... disorders: - Pale skin ... Insufficiency #Signs
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
manifestations Skin ... Inflammation of skin ... granulomas under skin ... pathophysiology #signs ... #symptoms #diagnosis
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... organ-specific signs ... or symptoms (eg ... , skin or esophageal ... Disorders #Algorithm #Differential
Chronic Abdominal Pain Causes - Differential Diagnosis Framework

Many patients with chronic abdominal pain have had prior
Causes - Differential ... • Skin changes ... • Urinary symptoms ... Abdominal cutaneous nerve ... #Differential #