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diagnosis hematology classification ana antibodies antinuclear chronic cll erythematosus hodgkins leukemia lymphocytic lymphoma management mds myelodysplasia myelodysplastic myopathy myositis patterns
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... disease • Non-autoimmune ... rheumatologic diseases ... deficiencies • Autoimmune ... : • Symptoms limited
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... • Richter’s Syndrome ... Leukemia #diagnosis #workup ... #oncology #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... such as systemic lupus ... Presentation - Systemic Symptoms ... purpura: strong sign ... #diagnosis #rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... age 70 years Symptoms ... Workup: • Complete ... blood count with differential ... #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunosuppression • Autoimmune ... ingestion • B symptoms ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... #oncology #management
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... #differential #
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