1188 results
Primary Adrenal Insufficiency:
 • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
Insufficiency: • ACTH stimulation ... production • CRH stimulation ... chronic lack of stimulation ... by ACTH • CRH stimulation ... endocrinology #workup
Adrenal Insufficiency Algorithm - Cosyntropin Stimulation Test
T-1m: Baseline cortisol drawn
T0: 250 µg cosyntropin given IV
T30m: Repeat
Adrenal Insufficiency ... - Cosyntropin Stimulation ... BCM_InternalMed #Adrenal ... #Cosyntropin #Stimulation
Adrenal Insufficiency - Differential Diagnosis Workup Algorithm
Primary Adrenal Insufficiency:
 • Autoimmune primary adrenal insufficiency
 • Adrenoleukodystrophy,
Adrenal Insufficiency ... Differential Diagnosis Workup ... Algorithm Primary Adrenal ... Autoimmune primary adrenal ... Differential #Diagnosis #Workup
Adrenal Insufficiency Diagnosis Algorithm
Clinical features: 
 - Weight loss, anorexia, Weakness, fatigue, GI distress
 - Hypotension,
Adrenal Insufficiency ... seen in PRIMARY adrenal ... suggestive of adrenal ... with cosyntropin stimulation ... #Cosyntropin #Stimulation
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Diagnosis and Workup ... HYPOVOLEMIC • extra-renal ... - fevers • renal ... hypothyroidism • adrenal ... Hypernatremia #Diagnosis #Workup
Workup for Hypophosphatemia - Differential Diagnosis Framework
Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia
Measure Urine Fractional Excretion
Workup for Hypophosphatemia ... Refeeding, Glycolysis stimulation ... FEPO4 ≥ 5% - Renal ... Diagnosis #Framework #Workup
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Adrenal Insufficiency ... hormone (ACTH) stimulation ... Cortisol Response - Adrenal ... ACTH - Primary adrenal ... ACTH - Secondary adrenal
Primary vs Secondary Adrenal Insufficiency - Pathophysiology
Primary AI = adrenal glands themselves are the problem. This
Primary vs Secondary Adrenal ... Pathophysiology Primary AI = adrenal ... leads to limited adrenal ... stimulation, thus ... Primary #Secondary #Adrenal
Diagnosis Adrenal Insufficiency - Algorithm

Step 1) Screening Test: 6-8AM Cortisol Level
 - Early morning cortisol levels
Diagnosis Adrenal ... Test: Cosyntropin Stimulation ... determines if the adrenal ... gland) #Adrenal ... Diagnosis #ACTH #Stimulation
Pulmonary Renal Syndrome: Investigations and Management

#Pulmonary #Renal #Syndrome #Diagnosis #Workup #Management
Pulmonary Renal ... #Pulmonary #Renal ... Syndrome #Diagnosis #Workup