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diagnosis differential rheumatology acute injury nephrology acidosis aki cryoglobulinemia cryoglobulins elevation erythematosus failure glomerulonephritis lactate lactic lupus postrenal prerenal progressive
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal PRE-RENAL Impaired perfusion: •
Causes of Acute ... Kidney Injury ( ... PRE-RENAL Impaired perfusion ... Glomerulonephritis Small-vessel ... vasculitis Acute
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Acute Kidney Injury ... - Classification ... emergency - Small ... vessel vasculitis ... tubular necrosis (causes
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
abnormalities SMALL ... tracts Immune Complex ... tract, and often causes ... pain, infarct • Small ... #rheumatology #classification
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... immunofluorescence Immune Complex ... • Limited to Kidney ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
deposit of immune complexes ... • They can cause ... Cryoglobulins Cause ... • Cutaneous small-vessel ... diagnosis #types #classification
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... musculoskeletal systems • Kidneys ... and infarcts SMALL ... pauci-immune GN Immune Complex ... tract, and often causes
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
/ hypoxemia -> focus ... on improving perfusion ... the patient’s complete ... Reduced tissue perfusion ... #typea #typeb #classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Lungs: • Pleural effusions ... inflammation of the small ... C4) • ds-DNA: Kidney ... induced SLE • Kidney
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