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management neurology differential gravis acetylcholinereceptor achr causes diplopia endocrinology hyperthyroidism intravenousimmunoglobulin ivig musclespecificreceptortyrosinekinase myastheniagravis myastheniccrisis myelitis ocularmyasthenia pef plasmapheresis ptosis
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Myasthenia Gravis ... chewing, loss of smile ... immunologic assay - MuSK ... Gravis Treatment ... #Gravis #diagnosis
Drugs associated with worsening of Myasthenia Gravis (MG): • D-penicillamine • Botulinum toxin. • Telithromycin • Fluoroquinolones • Quinine • Magnesium • Macrolide antibiotics • Corticosteroids (may cause transient
Gravis (MG): • ... Patients with MuSK-MG ... because of bulbar weakness ... muscle-specificreceptortyrosinekinase #AChR #MuSK ... #VC #NIF #PEF #
Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Myasthenia Gravis ... 50 years in men Diagnosis ... anti—muscle-specific kinase (MuSK ... antibodies - MuSK-positive ... #Gravis #diagnosis
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
irregularities • Weakness ... diffuse goiter (Graves ... antibodies (TRAb) if ... Graves' disease ... Cardiac arrhythmia
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Weakness: - Weakness ... bouts of HTN Diagnostic ... : • Must rule ... be tested and if ... Transverse Myelitis Treatment
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