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management differential causes injury kidney antipsychotic classification diuresis diuretics elevation encephalopathy excretion hyperkalemia hypokalemia k lactate lactic neonatal neurology oxoprolinuria
Medications causing Acute Kidney Injury (AKI) Prerenal: • Dehydration: Diuretics • Altered intrarenal autoregulation: ACEIs / ARBs,
Medications causing ... (AKI) Prerenal: ... sphincter tone: • Opiates ... #Drugs #pharmacology ... #differential #diagnosis
Acute Kidney Injury (AKI) - Differential Diagnosis Framework PRE-Renal AKI: • Hypovolemia • Congestion • Medications •
Acute Kidney Injury ... Diagnosis Framework ... Congestion • Medications ... Infection-mediated, Drug-induced ... #nephrology
Neonatal Resuscitation – Circulation and Drugs Consider drugs (k) if heart rate beats/min in spite of adequate
rate beats/min in spite ... perfusion due to acidosis ... vasoconstriction may have had acute ... haemorrhage or acute ... #Medications #Pharmacology
Vancomycin Associated Acute Kidney Injury • Drug induced acute kidney injury is generally defined as a
• Treatment includes ... #Vancomycin #AKI ... #pharmacology # ... toxicology #diagnosis ... #management #nephrology
Neurological Side Effects of Antipsychotic Drugs Acute dystonia - Spasm of muscles of tongue, face, neck, back
Acute dystonia ... Antiparkinsonian agents are diagnostic ... reduction; change medication ... #Medications #SideEffects ... #pharmacology #
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Etiology: • Medications ... , RTA Type IV, AI ... STOP offending medications ... #potassium #nephrology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
circulation If drugs ... before beginning treatment ... cardiac output - Acute ... peritonitis - Acute ... - HIV/HAART medications
5-Oxoprolinuria What is it: • Aka pyroglutamic acidosis, Intermediate in γ-glutamyl cycle • Amino acid transport and
What is it: • Aka ... pyroglutamic acidosis ... • Concomitant acute ... diabetes • Other drugs ... #management #treatment
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Neurological symptoms: Acute ... Electrolyte abnormality, Medication ... /Drug toxicity, ... syndrome, ADEM, Acute ... epilepticus Treatment
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
plasma insulin (treatment ... Renal tubular acidosis ... Conn's, Liddle's), Drugs ... Hypomagnesemia, Acute ... #nephrology
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