10 results
Drugs affecting the cardiac action potential. The sharp rise in voltage ("0") corresponds to the influx
Drugs affecting ... to the sodium-channel ... repolarizing eflux of potassium ... #Pathophys #Pharmacology ... Antiarrhythmics #Classes
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair ... Renal Potassium ... Decreased ENaC channel ... #Hyperkalemia #Pathophysiology ... #Pharmacology #
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Classification: CLASS ... 1 - Sodium Channel ... 3 - Potassium Channel ... Vaughan #Williams #Pharmacology ... #pathophysiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... Transient K+ efflux moving ... 3 - Potassium Channel ... Antiarrhythmics #Pharmacology ... #pathophysiology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... Heparin) • Sodium-channel ... differential #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Class III Antiarrhythmics - Potassium Channel Blockers - Indications and Side Effects
Amiodarone
 • Suppression of VT
Class III Antiarrhythmics ... - Potassium Channel ... a-flutter (when other drugs ... #Channel #Blockers ... #pharmacology #
Angiotensin Receptor Blockers 
Recommended Dose Conversions 

Valsartan 
Irbesartan 
Losartan 
Olmesartan 
Telmisartan 
Candesartan 
Azilsartan 
Eprosartan 

A few
in that class. ... recalls, this drug ... class is still ... for increased potassium ... #Pharmacology #
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Normal and Renal Dosing ... has very minimal chance ... class is that you ... This drug class ... #Pharmacology #
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
Cardiovascular Drug-Drug ... tachycardia Calcium Channel ... Bilberry, Danshen, Dong ... potential arrhythmias Class ... supplementals #herbal #pharmacology
Daliresp (Roflumilast) 
Indication: Reduce risk of COPD exacerbations 
Drug Class: Selective Phosphodiesterase-4 (PDE4) Inhibitor 
GOLD 2019
exacerbations Drug ... Class: Selective ... Eosinophils < 100 Dosing ... have been a few changes ... #Indications #Pharmacology