Specifiity visualabstract

Ohle R et al. Clinical Examination for Acute Aortic Dissection: A Systematic Review and Meta-analysis. AEM

#Sensitivity #Specificity ... #SGEM #VisualAbstract

POCUS for diagnosing the source of Sepsis - Visual Abstract
What is the accuracy of using point-of-care

Sensitivity - 73%, Specificity ... Sensitivity - 48%, Specificity ... diagnosis #ebm #visualabstract

Emergency physician interpretation of point-of-care ultrasound for identifying and grading of hydronephrosis in renal colic compared

29663580 #EBM #VisualAbstract ... #Sensitivity #Specificity

Accuracy of abdominal ultrasound for the diagnosis of small bowel obstruction in the emergency department

https://www.ncbi.nlm.nih.gov/pubmed/30181794

Our data

of 93.8% and a specificity ... sensitivity of 94.3% and specificity ... Abdominal #Ultrasound #VisualAbstract

Biliary POCUS for Cholecystectomy - Visual Abstract
What is the predictive value of biliary POCUS in terms

Sensitivity - 63% - Specificity ... diagnosis #ebm #visualabstract

POCUS for diagnosis of Aortic Dissection - Visual Abstract
What is the accuracy of point-of-care ultrasound evaluation

Sensitivity - 86% Specificity ... diagnosis #ebm #visualabstract

POCUS for diagnosis of Diverticulitis - Visual Abstract
What are the test characteristics of point-of-care ultrasonography in

Sensitivity - 97% Specificity ... diagnosis #ebm #visualabstract

Detection of Flexor Tenosynovitis on POCUS - Visual Abstract
Sensitivity - 94%
Specificity - 74%

Study: https://pubmed.ncbi.nlm.nih.gov/29396150/

#Flexor #Tenosynovitis #POCUS

Sensitivity - 94% Specificity ... diagnosis #ebm #visualabstract

3 Point POCUS for DVT - Visual Abstract
How accurately can emergency physicians diagnose lower extremity DVTs

Sensitivity - 93.2% - Specificity ... diagnosis #ebm #visualabstract

Lung POCUS for Diagnosis of CHF - Visual Abstract
What is the accuracy of combined Lung Ultrasound

Sensitivity - 93.5 - Specificity ... Sensitivity - 85.0 - Specificity ... diagnosis #ebm #visualabstract

Point of Care Ultrasound for Appendicitis - Visual Abstract

Can emergency physicians diagnose appendicitis with high specificity

appendicitis with high specificity ... Sensitivity 42.8% Specificity ... #Appendicitis #VisualAbstract ... #Sensitivity #Specificity

COVID19 Testing - PCR vs CT - Sensitivity and Specificity

Original Data via https://pubs.rsna.org/doi/full/10.1148/radiol.2020200642

Admission laboratory patterns in

Sensitivity and Specificity ... #Sensitivity #Specificity ... #Coronavirus #VisualAbstract

POCUS for diagnosis of Shoulder Dislocation - Visual Abstract
What is the sensitivity and specificity of point-of-care

sensitivity and specificity ... Sensitivity - 100% Specificity ... diagnosis #ebm #visualabstract

The value of point-of-care ultrasound for detecting nail bed injury in [the] ED

American Journal of Emergency

Ultrasound #EBM #VisualAbstract ... #Sensitivity #Specificity

POCUS for Ocular Ultrasound - Visual Abstract
How accurate is point-of-care ultrasound for diagnosing retinal detachment (RD),

Sensitivity 96.9, Specificity ... Sensitivity 81.9, Specificity ... Sensitivity 42.5, Specificity ... diagnosis #ebm #visualabstract

Lung POCUS for diagnosis of Acute Chest Syndrome (ACS) - Visual Abstract
How accurate is point of

Sensitivity: 87% - Specificity ... diagnosis #ebm #visualabstract

$FAST Exam for Hemorrhage in Pelvic Fractures - Visual Abstract Can the FAST exam detect clinically significant$

Sensitivity - 96% - Specificity ... diagnosis #ebm #visualabstract

POCUS for Small Bowel Obstruction - Visual Abstract
What is the accuracy of point of care ultrasound

Sensitivity - 88% Specificity ... diagnosis #ebm #visualabstract

POCUS Confirmation of Tracheal Intubation - Visual Abstract
How accurate is tracheal ultrasound in determining whether the

Sensitivity - 98.9% - Specificity ... diagnosis #ebm #visualabstract

POCUS Confirmation of CVC Placement - Visual Abstract
How accurate is a single view ultrasound protocol for

Sensitivity - 86.8% - Specificity ... diagnosis #ebm #visualabstract

Test Characteristics of Physical Exam, Imaging, and LRINEC
Score for the Identification of Necrotizing Fasciitis (Sensitivity,

(Sensitivity, Specificity ... #Sensitivity #Specifiity

Important Biostatistics and Epidemiology Equations

Sensitivity = TP / (TP + FN) = true positives / disease

disease present Specificity ... Sensitivity) / Specificity ... Sensitivity vs Specificity ... = Rule OUT - Specificity ... #sensitivity #specificity

Sensitivity Specificity False-Positive False-Negative Contingency Table / confusion matrix

Sensitivity refers to the test's ability to correctly

Sensitivity Specificity ... the condition Specificity ... Specificity of a ... #Sensitivity #Specificity

Urinalysis Testing - UTI Sensitivity and Specificity
- Leukocyte esterase
- Nitrite
- WBCs

Sensitivity and Specificity ... #Sensitivity #Specificity

lupusnephritis #anca #Visualabstract

Ascites: Physical Exam Diagnostic Accuracy

Sensitivity and Specificity: Shifting Dullness, Bulging Flanks. Fluid Wave

Source: Joseph D.

Sensitivity and Specificity ... #Sensitivity #Specificity

Tuberculous Pleural Effusions - Tests and Biomarkers
Age + fever + red blood cells + ADA -

sensitivity, high specificity ... sensitivity and specificity ... sensitivity and specificity ... sensitivity and specificity

#visualabstract

Summary of Major Trials of Steroids in Sepsis

- Vivek Moitra, MD
@vmoitra

#Steroids #Sepsis #Corticosteroids #EBM #Evidence #Trials

Evidence #Trials #VisualAbstract

Cholecystitis Diagnostic Test Characteristics

Sensitivity, Specificity and Likelihood Ratios of Labs, Physical Exam findings, and

Sensitivity, Specificity ... #Sensitivity #Specificity

Nephropathy #EBM #VisualAbstract

#Sensitivity #Specificity

Pulmonary #Embolism #VisualAbstract

Receptor actions of sympathomimetic and dopaminergic agents.
Adrenaline (epinephrine)
Noradrenaline (norepinephrine)
Isoprenaline
Dopamine
Dopexamine
Dobutamine

#Pharmacology #Vasopressors

Receptors #Targets #Specificity

POCUS Stewardship
Right Indication - Right Interpretation -Right Integration
Indication → Pre-test Probability → Spectrum of Disease →

→ Sensitivity, Specificity ... Sensitivity & Specificity ... sensitivity and specificity

CULPRITSHOCK #PCI #VisualAbstract

Magic Mouthwash for Oral Mucositis

https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2715162

Visual Abstract by Chanjun S Park @s_chanjun

#Magic #Mouthwash #Mucositis #EBM #VisualAbstract #Management

Mucositis #EBM #VisualAbstract

#Sensitivity #Specificity

$COMPARISON OF PREDICTION TOOLS FOR PREDICTING TBI IN PEDIATRIC PATIENTS - PECARN - CHALICE$

#Sensitivity #Specifiity

Randomised comparison of needle aspiration and chest tube drainage in spontaneous pneumothorax

Visual Abstract by Dr.

Management #EBM #VisualAbstract

Migraine #CGRP #VisualAbstract

Summary of the therapeutic uses of adrenergic agonists
Table of Catecholamine Pressors, Non-Catecholamines, Alpha and Beta Receptor

Receptors #Targets #Specificity

.2018.03.005 #EBM #VisualAbstract

Visual Abstract Comparison of #MYRE Vs #EULITE trials.

MYRE: https://jamanetwork.com/journals/jama/fullarticle/2665000
EULITE: https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(19)30014-6/fulltext

#MM #MultipleMyeloma #PLEX #VisualAbstract #Nephrology #EBM

MultipleMyeloma #PLEX #VisualAbstract

NegativeTrial #VisualAbstract

Ammonia Levels & Hepatic Encephalopathy in Patients with Chronic Liver Disease
Choosing Wisely: Things We Do

Hepatology #EBM #VisualAbstract

Metformin Treatment in Patients With Type 2 Diabetes and Chronic Kidney Disease Stages 3A, 3B, or

#Pharmacology #VisualAbstract

Glecaprevir and Pibrentasvir in Patients with HCV and Severe Renal Impairment #EBM #Hepatology #HCV #CKD #Glecaprevir

#Pibrentasvir #VisualAbstract

Woman – The TXA Trial for Post-Partum Hemorrhage. Lancet. 2017 May 27
https://www.ncbi.nlm.nih.gov/pubmed/28456509

#EBM #OBGyn #WOMANTrial #TXA

PostPartum #Hemorrhage #VisualAbstract

$Vertebroplasty versus sham procedure for painful acute osteoporotic vertebral compression fractures (VERTOS IV): randomised sham controlled$

CompressionFracture #VisualAbstract

Goal-Directed Therapy - Evidence Summary of Major Clinical Trials

- EGDT: NEJM 2001

- ProCESS: NEJM

#Trials #EBM #VisualAbstract

Effect of infographic promotion on research dissemination and readership

Source Article: https://www.ncbi.nlm.nih.gov/pubmed/28899440

#Infographic #Dissemination #VisualAbstract #EBM #Meded #Impact

Dissemination #VisualAbstract

Abdominojugular (Hepatojugular) Reflux

Described by Pasteur in 1885 as a physical sign of TR. Still useful for

sensitivity and specificity

►

Transfusion strategies for acute upper gastrointestinal bleeding - Visual Abstract

Villanueva Cetal. NEJM 2013 PMID 23281973 https://www.ncbi.nlm.nih.gov/pubmed/23281973

PulmCrit #EBM #VisualAbstract

The vital first ten minutes: Apgar scores and risks of cerebral palsy and epilepsy
#APGAR #pediatrics #peds

newborns #bmj #VisualAbstract

An AAV5 vector with a functional factor VIII gene tested in men with hemophilia A #EBM

GeneReplacementTherapy #VisualAbstract

Procalcitonin Guided Antibiotics in Sepsis

Efficacy and Safety of Procalcitonin Guidance in Patients With Suspected or Confirmed

Antibiotics #Sepsis #VisualAbstract

Mycophenolate Mofetil versus Cyclophosphamide for Induction Treatment of Lupus Nephritis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678035/

Mycophenolate versus Azathioprine as Maintenance Therapy

LupusNephritis #VisualAbstract

FOBT Testing in Hospitalized Patients with Upper GI Bleed
Choosing Wisely': Things We Do For No

TWDFNR #Diagnosis #VisualAbstract

Summary and links to five landmark trials of intensive control vs standard therapy in DM2:

UKPDS

18539917 #EBM #VisualAbstract

Fernando SM et al. Prognostic Accuracy of the Quick Sequential Organ Failure Assessment for Mortality in

#Sensitivity #Specificity

Hospitalization for the Evaluation of Patients with Low Risk Chest Pain
Choosing Wisely: Things We Do

Management #EBM #VisualAbstract

There are several screening questionnaires for OSA, although the accuracy of many of them is limited.4,6,7,24

than 85%, with a specificity ... , and a higher specificity

►

Validation of the “Step-by-Step” Approach in the Management of Young Febrile Infants
Visual Abstract by Dr. Kirsty

Peds #Pediatrics #VisualAbstract

Medicare versus VA Visual Abstract Sarah Gleeson @sarah_gleeson_
Dialysis Initiation and Mortality Among Older Veterans With Kidney

VeteransAffairs #VisualAbstract

Hydromorphone use for acute pain: Misconceptions, controversies, and risks. Motov et al
https://www.ncbi.nlm.nih.gov/pubmed/29508897

Visual Abstract by David Cisewski,

#Pharmacology #VisualAbstract

The AIRWAYS-2 Randomized Clinical Trial Infographic - A Visual Abstract

Effect of a Strategy of a Supraglottic

2698493 #EBM #VisualAbstract

Positive Anterior drawer test video

Test for ACL integrity. Knee at 90 degree pulling tibia forward. (+)

Test has >95% specificity

►

Sensitivity is the proportion of truly diseased persons in the screened population who are identified as

Specificity is the ... #Sensitivity #Specificity

►

SENSITIVITY & SPECIFICITY

Trials Comparing Short- vs Longer-Course Antibiotics
... Have Shown Short-Course is JUST AS EFFECTIVEI
Source Editorial:

Duration #EBM #VisualAbstract

Comparison of Resident and Faculty Perceptions of Burnout and Depression During Surgical Training

Do resident and

sarascarletMD #EBM #VisualAbstract

Serious Bacterial Illness (SBI):
1) UTI and pyelonephritis
Most common cause of SBI
Accounts for 3-8% of uncharacterized fevers
Female

Urinalysis: LE 75% specificity ... , Nitrites 97% specificity

Necrotizing Soft Tissue Infection: Diagnostic Accuracy of Physical Examination, Imaging, and LRINEC ScoreA Systematic Review and

#Sensitivity #Specificity

#VisualAbstract

The SALT Mass Casualty Triage Approach
- SALT stands for “Sort, Assess, Lifesaving interventions, and Treatment

regarding sensitivity, specificity

Trends in Inpatient Admission Comorbidity and Electronic Health Data: Implications for Resident Workload Intensity https://www.journalofhospitalmedicine.com/jhospmed/article/161383/hospital-medicine/trends-inpatient-admission-comorbidity-and-electronic

Visual Abstract

WrayCharles #EBM #VisualAbstract

Association of an Opioid Standard of Practice Intervention With Intravenous Opioid Exposure in Hospitalized Patients

Source Article:

Intravenous #Pain #VisualAbstract

Sgarbossa’s ECG criteria for detecting ischemia in the presence of left bundle branch block (LBBB)

The Sgarbossa

of 20–36% and specificity

Extent of Myocardial Ischemia on Positron Emission Tomography and Survival Benefit With Early Revascularization

1. In this

.2minutemedicine.com/visualabstract-extent-of-myocardial-ischemia-on-positron-emission-tomography-and-survival-benefit-with-early-revascularization ... Revascularization #EBM #VisualAbstract

Algorithm to decrease AFib admissions - Visual Abstract by hellomynameisDrKirsty
@KirstyChallen

Source: Implementation of a Novel Algorithm to

Fibrillation #Protocol #VisualAbstract

SALT-ED Trial - Balanced Crystalloids versus Saline in Noncritically Ill Adults

N Engl J Med 2018; 378:819-828

#AKI #MAKE30 #VisualAbstract

Outcomes in Severe Hyponatremia Treated With and Without Desmopressin.

Am J Med. 2018 Mar;131(3):317.e1-317.e10. doi: 10.1016/j.amjmed.2017.09.048. Epub

Outcomes #amjmed #VisualAbstract

PARAMEDIC2 Trial Visual Abstract:
Adrenaline vs. Placebo in out-of-hospital
- Tommaso Scquizzato
@tscquizzato

https://www.nejm.org/doi/full/10.1056/NEJMoa1806842
A Randomized Trial of

Arrest #EBM #VisualAbstract

The Evidence for Aspirin - Visual Abstract

Three new aspirin trials in three different populations:
-

mortality #Aspirin #VisualAbstract

Rate of Correction of Hypernatremia and Health Outcomes in Critically Ill Patients

CJASN May 2019, 14 (5)

EBM #Nephrology #VisualAbstract

COVID-19 - Awake Self-Proning

Physiology of proning:
- more homogenous ventilation
- decrease ventral-dorsal transpulmonary pressure difference

management #treatment #VisualAbstract

PIVOTAL Visual Abstract - Intravenous Iron in Patients Undergoing Maintenance Hemodialysis - January 31, 2019

N Engl

Intravenous #IVIron #VisualAbstract

Alveolar Recruitment
Effect of Intensive vs Moderate Alveolar Recruitment Strategies Added to Lung-Protective Ventilation on Postoperative Pulmonary

Recruitment #EBM #VisualAbstract

Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
• Polysaccharide cell wall component of many fungi
• Pathogens:

Sensitivity & Specificity ... 96% - Higher specificity ... Sensitivity & Specificity

The test characteristics of the heterophile antibody (AKA the monospot test) are not perfect and can

#Sensitivity #Specificity

Two-Unit Red Cell Transfusions in Stable Anemic Patients
Choosing Wisely: Things We Do For No Reason

https://www.journalofhospitalmedicine.com/jhospmed/article/145147/hospital-medicine/things-we-do-no-reason-two-unit-red-cell-transfusions

#Transfusion

Management #EBM #VisualAbstract

Continuous B-cell depletion in frequently relapsing, steroid-dependent and steroid-resistant nephrotic syndrome

Clinical Kidney Journal, , sfy067,

BCell #Depletion #VisualAbstract

Commonly Used Diagnostic Tests for Celiac Disease

Tissue transglutaminase (tTG) IgA antibodies
- Most reliable noninvasive test

sensitivity and specificity ... sensitivity and specificity

TOPCAT - Spironolactone for Heart Failure with Preserved Ejection Fraction

N Engl J Med 2014; 370:1383-1392 https://www.nejm.org/doi/10.1056/NEJMoa1313731

CONCLUSIONS:

Cardiology #EBM #VisualAbstract

CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
•

sensitivity 100%, specificity ... at 50–90%, but specificity ... 80–90%, and a specificity ... sensitivity 92% and specificity

Decompressive Craniectomy in Diffuse Traumatic Brain Injury (DECRA)

In adults with severe diffuse traumatic brain injury and

Decompressive #TBI #VisualAbstract

Pronator Drift Testing for Stroke
Subtle extensor weakness - Sign of Upper motor neuron lesion
In detecting CT/MRI

Sensitivity 92%, Specificity

NICE-SUGAR - Intensive versus Conventional Glucose Control in Critically Ill Patients
N Engl J Med 2009; 360:1283-1297

Endocrinology #VisualAbstract

Mortality after Fluid Bolus in African Children with Severe Infection - June 30, 2011 N Engl

#Africa #NEJM #VisualAbstract

POLAR Randomized Clinical Trial - Effect of Early Sustained Prophylactic Hypothermia on Neurologic Outcomes Among Patients

CriticalCare #ICU #VisualAbstract

#AKIKI #Trial #VisualAbstract

Management #EBM #VisualAbstract

Randomized Clinical Trial of IV Acetaminophen as an Analgesic Adjunct for Older Adults with Acute Severe

Dilaudid #EBM #VisualAbstract

The HYPERION Trial - Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm - Visual Abstract

NEJM

CardiacArrest #VisualAbstract

ACUTE CHOLANGITIS
Legend says that Cholangitis was first defined in 1877 by Jean-Martin Charcot, at which time

triad has a high specificity ... sensitivity of 100% and specificity

Efficacy and safety of quetiapine in critically ill patients with delirium: a prospective, multicenter, randomized, double-blind,

Delirium #EBM #VisualAbstract

$Evidence supports the Ottawa ankle rules as an accurate instrument for excluding fractures of the ankle$

100% and a modest specificity

Airway Pressure Release Ventilation (APRV) - Early application of airway pressure release ventilation may reduce the

Ventilation #ARDS #VisualAbstract

Contact Precautions for MRSA & VRE
Choosing Wisely: Things We Do For No Reason

Source Article: https://www.journalofhospitalmedicine.com/jhospmed/article/195053/hospital-medicine/things-we-do-no-reason-contact-precautions-mrsa-and-vre
Rebuttal

InfectiousDiseases #EBM #VisualAbstract

PAMPER - Prehospital Plasma during Air Medical Transport in Trauma Patients at Risk for Hemorrhagic Shock

N

#CriticalCare #VisualAbstract

1,3 Beta-D-Glucan and Galactomannan - Pathogens, and Testing Characteristics
1,3 ß-D-glucan:
• Most fungi excluding mucor and

#Sensitivity #Specificity

Diagnostic Testing for Meningitis
History:
• Triad: Fever, neck stiffness, and altered mental status
• Sens: 44%

#Sensitivity #Specificity

PROSEVA definition of ARDS
Thus, the PROSEVA trial essentially modifies the Berlin definition of ARDS, with the

This improves the specificity

►

Diagnostic algorithm for the workup of hypercalcemia. The diagnostic workup for patients presenting with hypercalcemia rests

) was 0.80 and specificity

Visual Abstract - Rocuronium vs. Succinylcholine for Pre-hospital Rapid Sequence Intubation

JAMA. 2019;322(23):2303-2312. doi:10.1001/jama.2019.1825 https://jamanetwork.com/journals/jama/article-abstract/2757578

Useful commentary on

Succinylcholine #VisualAbstract

Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -

Thresholds #Hematology #VisualAbstract

IDEALICU #Trial #VisualAbstract

#ELAIN #Trial #VisualAbstract

ROTH Score to Assess O2 Sat for Telemedicine

Have pt take deep breath in & count out

Sensitivity of 87 % - Specificity

REVISE - Withholding Pantoprazole for Stress Ulcer Prophylaxis in Critically Ill Patients: A Pilot Randomized Clinical

#Withholding #VisualAbstract

Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction

CONCLUSIONS:
Among patients with heart failure and a

Dapagliflozin #hfref #chf #visualabstract

Bystander Efforts and 1-Year Outcomes in Out-of-Hospital Cardiac Arrest

N Engl J Med 2017; 376:1737-1747 https://www.nejm.org/doi/full/10.1056/NEJMoa1601891

Conclusion: Bystander

Bystander #CPR #VisualAbstract

Point-of-care Ultrasound for Diagnosis of Abscess in Skin and Soft Tissue Infections

1. POCUS is more accurate

Diagnosis #Exam #VisualAbstract

POCUS for diagnosis of Wall Motion Abnormalities in Myocardial Infarction - Visual Abstract
Can physicians with limited

diagnosis #ebm #visualabstract

Balanced Crystalloids vs. NormalSaline - My infographic about SALT-ED and SMART trial comparing crystalloids and saline

#Saline #AKI #VisualAbstract

Selected Clinical Trials of SGLT2 inhibitors in CVD and CKD
EMPA-REG OUTCOME - Empagliflozin lowered CV events

inhibitors #EBM #trial #visualabstract

Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is

and uncertain specificity

Diagnosis Adrenal Insufficiency - Algorithm

Step 1) Screening Test: 6-8AM Cortisol Level
- Early morning cortisol levels

have almost 100% specificity

Practice Guidelines for Preoperative Fasting

Infographic by Dr. Jesse Burk-Rafel
@jbrafel

> 8 hours - Heavy foods (fried/fatty) and

Timeline #EBM #VisualAbstract

sensitivity and specificity

Lewy Body Dementia: Pathogenesis and Clinical Findings
Lewy Body Dementia is a sub-category of major or mild

of diagnostic specificity

Cardiac Arrest #visualabstract

#VisualAbstract

Effect of Lung Recruitment and Titrated Positive End-Expiratory Pressure (PEEP) vs Low PEEP on Mortality in

PEEP #ARDS #EBM #VisualAbstract

CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus

sensitivity and specificity ... sensitivity and specificity

TTH48 - Targeted Temperature Management for 48 vs 24 Hours and Neurologic Outcome After Out-of-Hospital Cardiac

CriticalCare #ICU #VisualAbstract

CULPRIT-SHOCK Visual Abstract Infographic

PCI Strategies in Patients with Acute Myocardial Infarction and Cardiogenic Shock

https://www.nejm.org/doi/full/10.1056/NEJMoa1710261

CONCLUSIONS: Among

Multivessel #EBM #VisualAbstract

How to use C-reactive protein (CRP)- Review https://ep.bmj.com/content/early/2018/07/19/archdischild-2018-315079

- An CRP alone cannot be used to

CReactiveProtein #VisualAbstract

SHoC-ED - Does Point-of-Care Ultrasonography Improve Clinical Outcomes in Emergency Department Patients With Undifferentiated Hypotension?

Ann

#CriticalCare #VisualAbstract

The WOMAN Trial (World Maternal Antifibrinolytic Trial): tranexamic acid for the treatment of postpartum haemorrhage: an

PostPartum #Hemorrhage #VisualAbstract

Streptocccus Pneumoniae
Microbiology: Gram Positive, Alpha-hemolytic, Catalase Negative
Epidemiology - 10% adult carriers:
• Most common cause of:

Sensitivity 82%, Specificity

Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins

Rigors) showed a specificity

Group A Strep Pharyngitis, also known as Strep Throat.

In addition to symptomatic presentation, a

post regarding specificity

Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:

citrullinated peptide) - ↑ specificity

Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,

S 64-79%), 95% specificity

1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
• Cell wall component of many fungi

Testing Sensitivity Specificity ... 96% • Higher specificity

Hydroxyapatite Deposition Disease (HADD) - MSK Radiology
Imaging Findings:
• Ovoid hypointense structures along the bursal surface

pathology (i.e. lower specificity

Clinical Trial of Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis - Kupperman et al. NEJM 2018

https://www.nejm.org/doi/full/10.1056/NEJMoa1716816
Study

TessaRDavis #EBM #VisualAbstract

Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
• R >

Assists in liver specificity

Randomized study of IV prochlorperazine plus diphenhydramine vs IV hydromorphone for migraine
https://www.ncbi.nlm.nih.gov/pubmed/29046364

Visual Abstract by David Cisewski,

Migraine #EBM #VisualAbstract

D-dimer
Plasma D-dimer is a product of clot breakdown, released upon degradation of polymerized, crosslinked fibrin. Elevated

can cause a ↓ specificity ... Specificity can ... yrs of age) the specificity

Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout

sensitivity and specificity

Capnocytophaga
Pathogen: Capnocytophaga
• 9 species, C. canimorsus responsible for the majority of infections
• Gram-negative rod,

Sensitivity and specificity

USMLE Epidemiology and Biostatistics Summary
Meta-Analysis: pools data from several studies (greater power), limited by quality/bias of

Specificity (rule ... FN) Higher specificity

Balloting the ETT cuff refers to exerting gentle bouncing pressure over the suprasternal notch while palpating

has only a 26% specificity

Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury:
• Hepatic vein:

Assists in liver specificity

Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused

sensitivity and low specificity

Positive Anterior drawer test video: Test for ACL integrity. Knee at 90 degree pulling tibia

Test has >95% specificity

►

Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of

testing has higher specificity

$Esmolol in Refractory Ventricular Fibrillation - Visual Abstract by Sparsh Shah @sparsh717 * Use of esmolol after failure$

27523955 #EBM #VisualAbstract

Effect of Dexmedetomidine on Mortality and Ventilator-Free Days in Patients Requiring Mechanical Ventilation With Sepsis

JAMA. 2017;317(13):1321-1328

CriticalCare #EBM #VisualAbstract

ProCESS Investigator - A Randomized Trial of Protocol-Based Care for Early Septic Shock

N Engl J Med

Protocol #Sepsis #VisualAbstract

FABER Maneuver: Flexion, ABduction, External Rotation

Tips to distinguish SI joint pain from other areas of

sensitivity=0.60-0.77, specificity

Sensitivity and Specificity of KUB compared to CT for Bowel Obstruction, Urolithiasis, Appendicitis, Pyelonephritis, Pancreatitis, Diverticulitis
Comparison

Sensitivity and Specificity ... #Sensitivity #Specificty

Sensitivity and Specificity

Specificity Calculation - Probability that a test correctly identifies those without the disease (true negative rate)

Specificity

Specificity Calculation ... negative rate) Specificity ... TN / (FP + TN) Specificity ... = Rule IN #Specificity

#visualabstract

#VisualAbstract

#visualabstract

#VisualAbstract

Acute Mesenteric Ischemia - Performance of
Laboratory Tests (Sensitivity, Specificity)
- WBC, Lactate, D-dimer, Urine I-FABP

#Mesenteric

(Sensitivity, Specificity ... #Sensitivity #Specificity

magicapp #bmj #visualabstract

#visualabstract

#VisualAbstract

$#visualabstract #DAPA-CKD #dapagliflozin$

#visualabstract

Hunter's Decision Rule (Sensitivity 84%, Specificity 97%), Sternbach's criteria - Need 3 of 10 symptoms: (Sensitivity

Sensitivity 84%, Specificity ... Sensitivity 75%, specificity

HFNC) #clinical #visualabstract

dialysis #nephrology #VisualAbstract

"Imagine you're running airport security, screening passengers (tests) to catch dangerous items (diseases). Now meet your

Sensitivity and Specificity ... Specificity, on ... test has high specificity ... High specificity ... #medicine #specificity

Catheter-Directed Thrombolysis for Deep-Vein Thrombosis #EBM #CatheterDirectedThrombolysis #PostThromboticSyndrome #NegativeTrial #VisualAbstract #NEJM

NegativeTrial #VisualAbstract

Tofacitinib #Adalimumab #VisualAbstract

Dr. Kirsty Challen summarizes the ADRENAL Trial - hellomynameiskirsty @KirstyChallen
#EBM #ADRENAL #Hydrocortisone #Corticosteroids #SepticShock #NEJM #VisualAbstract

SepticShock #NEJM #VisualAbstract

Long-Term Effects of Inhaled Budesonide for Bronchopulmonary Dysplasia #EBM #Peds #Budesonide #BronchopulmonaryDysplasia #BPD #VisualAbstract #NEJM

BronchopulmonaryDysplasia #BPD #VisualAbstract

It's eye-opening to realize how many tests with reasonable-appearing sensitivity or specificity will end up being

sensitivity or specificity ... despite having a specificity ... #Sensitivity #Specificity

Performance Characteristics for Colorectal Cancer Screening Tests
Stool/blood-based tests:
• FIT: 79% sensitivity, 94% specificity for CRC

sensitivity, 94% specificity ... sensitivity, 87% specificity ... sensitivity, 91% specificity ... sensitivity, 93% specificity

Aspirin #COMPASS #VisualAbstract

Cytosorb

BLOOD PURIFICATION TECHNIQUES

EXTRACORPOREAL CYTOKINE REMOVAL

Infographic by Dr. Catherine Beni @totalbodydolor

#Cytosorb #CYTOKINE #REMOVAL

REMOVAL #ACESS #VisualAbstract

Bivalirudin versus Heparin Monotherapy in Myocardial Infarction (VALIDATE-SWEDEHEART) #EBM #Cardiology #VALIDATE #SWEDEHEART #Bivalirudin #Heparin #PCI #VisualAbstract

#Heparin #PCI #VisualAbstract

Tezacaftor–Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del #EBM #CysticFibrosis #Tezacaftor #Ivacaftor #CFTR #Phe508del #NEJM

Phe508del #NEJM #VisualAbstract

Sensitivity 89%, Specificity

Comparison of Syncope Rules

#EBM #Diagnosis #Cardiology #Comparison #Table #Syncope #Rules #SanFrancisco #OESIL #Boston #Rose #ALiEM

#Sensitivity #Specificity

ACA Colorectal Cancer Screening Guidelines

When to Screen?
When to Stop?
Family History

Performance Characteristics for Colorectal Cancer Screening Tests
Stool/blood-based

sensitivity, 94% specificity ... sensitivity, 87% specificity ... sensitivity, 91% specificity ... sensitivity, 93% specificity

Accuracy of Computed Tomography Findings for the Diagnosis of Acute Diverticulitis

#Diagnosis #Radiology #CT #ComputedTomography #Diverticulitis #Findings

#Sensitivity #Specificity

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Alectinib versus Crizotinib in Untreated ALK-Positive Non–Small-Cell Lung Cancer #EBM #Honc #Alectinib #Crizotinib #ALK #ALKPositive #NSCLC

ALKPositive #NSCLC #VisualAbstract

Point of Care Ultrasound (POCUS) Diagnostic Accuracy in Small Bowel Obstruction (SBO)

#SBO #Accuracy #POCUS #SmallBowel #Obstruction

#Sensitivity #Specificity

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Neonatal COVID-19 Infection

https://jamanetwork.com/journals/jamapediatrics/fullarticle/2763787

By Heather Lin @hklin3, Rebecca Steinberg @RebeccaSteinb17

#Neonatal #COVID19 #VisualAbstract #Infection #Peds #Pediatrics

Neonatal #COVID19 #VisualAbstract

Diagnostic Accuracy of Electrocardiographic Criteria for Left Ventricular Hypertrophy Circulation 2009 #EBM #Diagnosis #Cardiology #LVH #Hypertrophy

#Sensitivity #Specificity

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PARIS Trial: A Randomized Trial of High-Flow Oxygen Therapy in Infants with Bronchiolitis
#EBM #Peds #Pediatrics #Bronchiolitis

dontforgetthebubbles #VisualAbstract

Diagnostic Approach to Subarachnoid Hemorrhage

Visual Abstract Article: https://www.bmj.com/content/343/bmj.d4277.long

#Subarachnoid #Hemorrhage #SAH #VisualAbstract #Diagnosis #Ruleout #Timing #Sensitivity

Hemorrhage #SAH #VisualAbstract

ICU Intubation - Severe Complication Rates

Optimise, don't compromise: peri-intubation physiology

- Dr. Steve Mathieu https://twitter.com/stevemathieu75

#ICU #Intubation

#DecisionAid #VisualAbstract

Original and Simplified PESI Prediction Rule Test Characteristics for 30-Day Mortality
#EBM #Diagnosis #EM #IM #PCC #PESI #sPESI #risk

#Sensitivity #Specificity

Guideline for Ultrasound Transducer Cleaning and Disinfection
- ACEP Policy Statement

https://www.annemergmed.com/article/S0196-0644(18)30668-1/fulltext

#Transducer #Cleaning #Disinfection #POCUS #Ultrasound #Policy

#Policy #ACEP #VisualAbstract

#visualabstract

AndrewMIbrahim #EBM #VisualAbstract

A Cluster-Randomized Trial of Blood-Pressure Reduction in Black Barbershops
http://www.nejm.org/doi/full/10.1056/NEJMoa1717250
- Visual Abstract - Usama Nasir @usamanasir311
#EBM

Hypertension #NEJM #VisualAbstract

A Cluster-Randomized Trial of Blood-Pressure Reduction in Black Barbershops
http://www.nejm.org/doi/full/10.1056/NEJMoa1717250 - Visual Abstract - Michelle Lim

Hypertension #NEJM #VisualAbstract

This requires defining some general cutoff values for likelihood ratios. These are admittedly arbitrary, but

between sensitivity/specificity ... #Sensitivity #Specificity

COVID-19: Silent Spread

T. Tyler Daugherty, MS4 @daughertyler and Stephen Gurley, MS4 @GurleyGuy

Source Article: https://www.cdc.gov/mmwr/volumes/69/wr/mm6913e1.htm?s_cid=mm6913e1_w

#COVID19 #Silent #Asymptomatic

Spread #Carriers #VisualAbstract

Seth Trueger
@MDaware - which drunks in the ED are hiding badness? by @jonbcole2 @brian_driver @RJelinek @hcmcEM

CriticalIllness #VisualAbstract

#Visualabstract for the BICAR-ICU trial LANCET

"Sodium bicarbonate therapy for patients with severe metabolic acidaemia in

#Visualabstract ... Acidemia #Acidosis #VisualAbstract

Major Adverse Events and Relationship of NPO Status in Pediatric Sedation/Anesthesia Outside the Operating Room

Source Paper:

Sedation #EBM #VisualAbstract

Predicting Failure of Outpatient Oral Antibiotics for Cellulitis

Odds Ratios by symptoms: Fever, Chronic Leg Ulcers, Edema,

Cellulitis #EBM #VisualAbstract

Inhaled isopropyl alcohol for nausea

Aromatherapy Versus Oral Ondansetron for Antiemetic Therapy Among Adult Emergency Department

#Swab #Nausea #VisualAbstract

Spironolactone Versus Clonidine as a Fourth-Drug Therapy for Resistant Hypertension: The ReHOT Randomized Study (Resistant Hypertension

pubmed/29463627 #VisualAbstract

Neutropenic Diet
Choosing Wisely: Things We Do For No Reason

https://www.journalofhospitalmedicine.com/jhospmed/article/166593/hospital-medicine/things-we-do-no-reason-neutropenic-diet

Visual Abstract by Dr. Arjun Gupta https://twitter.com/guptaarjun90

#NeutropenicDiet

Management #EBM #VisualAbstract

Review of Intranasally Administered Medications for Use in the Emergency Department
Table of agents, uses, dosing, onset

Table #Dosing #VisualAbstract

SGEM#204: Hold the Line – IVs Aren’t Always Required. Hawkins et al. Peripheral Intravenous Cannula Insertion

Reduction #AEM #SGEM #VisualAbstract

Breakfast and weight loss - BMJ Visual Abstract

Reviewing the effects of breakfast consumption
on body weight

Breakfast #WeightLoss #VisualAbstract

Intravenous subdissociative-dose ketamine versus morphine for acute geriatric pain in the Emergency Department: A randomized controlled

#GERIKET #EBM #VisualAbstract

Toradol - Analgesic Ceiling

Motov, S, Yasavolian, M, Likourezos, A, et al. Comparison of Intravenous Ketorolac at

Ceiling #Dosing #VisualAbstract

Small Bowel Obstruction on POCUS

SBO diagnosis in minutes of patients arrival to ED, "to/fro peristalsis" (aka

Specificity ~ 90

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SGEM#210: (Don’t) Let it Bleed – TXA for Epistaxis in Patients on Anti-Platelet Drugs. Zahed et

AntiplateletDrugs #SGEM #VisualAbstract

RESCUEicp - Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension

Stacked Bar Chart of Extended Glasgow Outcome

GOSE #Outcomes #VisualAbstract

Chronic Hep B - How to screen for HCC
-q6 months ultrasounds
-Use of AFP has been found

sensitvity nad specificity

Apixiban vs. Warfarin for Atrial fibrillation in Patients on Dialysis: A Retrospective Cohort

Conclusion: In this

atrialfibrillation #dialysis #visualabstract

$Esmolol for Refractory Ventricular Fibrillation - Visual Abstract by Mike O'Brien @MikeEMPharmD * Use of esmolol after failure$

27523955 #EBM #VisualAbstract

APRV in ARDS - A Visual Abstract

Early application of airway pressure release ventilation may reduce the

Ventilation #ARDS #VisualAbstract

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Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest - TTM2 Visual Abstract

https://www.nejm.org/doi/full/10.1056/NEJMoa2100591

Conclusion: In patients with coma

CardiacArrest #VisualAbstract

Sputum Purulence Spectrum

A study by Soler (2007) compared bronchoscopic sputum culture results of those hospitalized with

sensitivity of 89.5% and specificity

Randomized Controlled Trial of Intravenous Acetaminophen Versus Intravenous Hydromorphone for the Treatment of Acute Pain in

dhcisewski #EBM #VisualAbstract

LOWMAGHI - Magnesium for Afib Rate Control

LOw dose MAGnesium sulfate versus HIgh dose in the early

Fibrillation #EBM #VisualAbstract

Transfusion Strategies for Acute Upper GI Bleeding

Conclusion: As compared with a liberal transfusion strategy, a restrictive

UpperGI #GIBleeding #VisualAbstract

ATHOS-3 - Angiotensin II for the Treatment of Vasodilatory Shock

Khanna A et al. "Angiotensin II for

AngiotensinII #VisualAbstract

$SGEM#216: Pump It Up – Corticosteroids for Patients with Pneumonia Admitted to Hospital. Stern A et$

CochraneReview #VisualAbstract

Traumatic intracranial injury in intoxicated patients with minor head trauma.
Visual Abstract by Dr. David Cisewski @dhcisewski
Acad

#EBM #VisualAbstract

Ultrasound and Delays in Chest Compressions - Visual Abstract
Does POCUS during cardiac arrest lead to longer

diagnosis #ebm #visualabstract

Outcomes of CPR in COVID-19 Patients who arrest in the hospital

- 136 patients had CPR attempted
-

DecisionAid #EBM #VisualAbstract

CHEETAH - Levosimendan for Hemodynamic Support after Cardiac Surgery

N Engl J Med 2017; 376:2021-2031 https://www.nejm.org/doi/full/10.1056/NEJMoa1616325

Conclusion: In

#Levosimendan #VisualAbstract

POCUS for Posterior Ocular Ultrasound - Visual Abstract
What are the test characteristics of POCUS in diagnosing

diagnosis #ebm #visualabstract

POCUS for diagnosis of Dyspnea - Visual Abstract
How accurate is combined heart, lung, and IVC ultrasound

diagnosis #ebm #visualabstract

REPRISE Trial - Tolvaptan in CKD - Visual Abstract

Does tolvaptan slow the progression of autosomal dominant

REPRISE #Trial #CKD #VisualAbstract

Visual Abstract: Does lung ultrasound compared to standard approach, improve the accuracy for diagnosis of acute

CHF #ADHF #EBM #VisualAbstract

POCUS in Preeclampsia - Visual Abstract
What is the prevalence of abnormalities diagnosed on POCUS in women

diagnosis #ebm #visualabstract

Lower Extremity Peripheral Artery Disease (PAD)
PAD affects >230 million adults worldwide & is associated with increased

sensitivity 68-84% & specificity

(1,3)-β-d-glucan
Abundant cell wall polysaccharide, found in most fungi, except cryptococci, zygomycetes (mucor, rhizophus) and blastomyces.
Sensitivity 64%-93%;

Sensitivity 64%-93%; Specificity

Intravenous Lidocaine for Intractable Renal Colic Unresponsive to Standard Therapy
Sin B, Cao J, Yang D, Ambert

Lidocaine #RenalColic #VisualAbstract

Nonsedation or Light Sedation in Critically Ill, Mechanically Ventilated Patients - Visual Abstract

CONCLUSIONS: Among mechanically ventilated

#CriticalCare #VisualAbstract

Lidocaine #RenalColic #VisualAbstract

Normal Lung Sliding in the case of Bullous Lung Disease

Patient presents with with Rt chest pain/dyspnea.

sensitivity and 100% specificity

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The Febrile Infant Step-by-Step Algorithm
This is an algorithm developed by European emergency physicians to identify low-risk

Sensitivity and specificity

Video Laryngoscopy vs Direct Laryngoscopy on Successful First-Pass Orotracheal Intubation Among ICU Patients

JAMA. 2017;317(5):483-493 https://jamanetwork.com/journals/jama/fullarticle/2598718

Conclusions: Among

#Success #EBM #VisualAbstract

Evaluation of early administration of simvastatin in the prevention and treatment of delirium in critically ill

CriticalCare #EBM #VisualAbstract

Intraoperative Norepinephrine to Control Arterial Pressure (INPRESS) Study

Effect of Individualized vs Standard Blood Pressure Management Strategies

BloodPressure #Strategy #VisualAbstract

Pain Profiles: Ketorolac and Morphine in Renal Colic - David Cisewski, MD @DHCisewski / @PainProfiles

Efficacy

Morphine #RenalColic #VisualAbstract

SMART Trial - Balanced Crystalloids versus Saline in Critically Ill Adults

N Engl J Med 2018;

Crystalloids #Saline #VisualAbstract

#Epilepticus #VisualAbstract

RELIEF - Restrictive versus Liberal Fluid Therapy for Major Abdominal Surgery

N Engl J Med 2018;

Wilkinsonjonny #EBM #VisualAbstract

Summary of Available Tests for Clostridium difficile Infection, in Decreasing Order of Sensitivity
• Toxigenic culture

testing #sensitvity #specificity

CAGE Mnemonic - Alcohol Screening Tool

C - Cut down - Have you ever felt you needed

sensitivity, 77% specificity

A Comparison of Headache Treatment in the Emergency Department: Prochlorperazine Versus Ketamine
Zitek T, Gates M, Pitotti

Compazine #Comparison #VisualAbstract

Effects of prophylactic anticholinergic medications to decrease extrapyramidal side effects in patients taking acute antiemetic drugs:

#Antiemetics #VisualAbstract

Small Bowel Obstruction on POCUS

This 28yo female with history of Crohn's disease presents with abdominal pain,

sensitivity & specificity

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A prospective randomized, double-dummy trial comparing IV push low dose ketamine to short infusion of low

Comparison #Versus #VisualAbstract

Edoxaban for the Treatment of Cancer-Associated Venous Thromboembolism

https://www.nejm.org/doi/full/10.1056/NEJMoa1711948

Authors’ Conclusions: “Oral edoxaban was noninferior to subcutaneous dalteparin

VenousThromboembolism #VTE #EBM #VisualAbstract

Intravenous versus oral paracetamol for acute pain in adults in the emergency department setting: a prospective,

Tylenol #APAP #VisualAbstract

sensitivity and specificity

Strongyloides Stercoralis
EPIDEMIOLOGY - ASSOCIATED WITH SOUTHEASTERN U.S.:
• 0-6% US Prevalence of those:
• ~30% Asymptomatic

sensitivity and specificity

Pathergy Summary Overview

What is pathergy?
Pathergy is an exaggerated skin injury occurring after minor trauma such as

• 97% specificity

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