12 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... gastric bypass), LFT ... #Causes #Workup ... #hematology
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Underproduction Diagnostic ... Probable bone marrow disorder ... - TSH, LFTs, ... Underproduction #Algorithm #hematology ... #workup
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Schistocytes, thrombocytopenia ... Consider RBC membrane disorder ... #Algorithm #workup ... #hematology #testing
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... late adulthood • Diagnosis ... specifically immune thrombocytopenia ... conditions Diagnosis ... hypogammaglobulinemia #immunology #hematology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... measuring vWF level ... Gplb receptor • Thrombcytopenia ... #hematology #hemepath ... #differential #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
leukemia in adults • Disorder ... minimal tumor burden Diagnosis ... ) B symptoms → fevers ... Leukemia #oncology #hematology ... #hemeonc #diagnosis
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... activity is the diagnostic ... available for rapid diagnosis ... and fibrinogen levels ... #Workup #Hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... function tests (LFTs ... metabolic or endocrine disorders ... (to support a diagnosis ... #diagnosis #testing
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... lymphoproliferative disorders ... Neutropenia, anemia, thrombocytopenia ... #workup #oncology ... #hematology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
syndrome (SFTS) ... Histopathological Diagnoses ... immunoglobulin levels ... agonists #TAFRO #diagnosis ... #management #rheumatology