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diagnosis hematology causes algorithm hemolytic oncology agglutinin classification cold disease eosinophil eosinophilia gap globulin hodgkins hypertension indications lymphoma management mds
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Diagnosis Secondary ... malignancies • Anemia ... iron deficiency, hemolysis ... Chronic inflammatory disorders ... #secondary
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Consider RBC membrane disorder ... #Anemia #Differential ... Diagnosis #Algorithm #workup
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
AIHA Primary Secondary ... Secondary Cold ... anemia • Cold ... younger pts) Differential ... #anemia #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... during medical evaluation ... • Screen for secondary ... #Algorithm #Differential ... #diagnosis #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory Evaluation ... anemia Indirect ... WBC count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... leakage of RBC's secondary ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... #nonpalpable #dermatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... Diagnosis and Workup ... changes), high MCV anemia ... - Bone marrow evaluation ... #hematology
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
Causes of Secondary ... Hypertension - Workup ... and Differential ... Approach (when evaluation ... Neurologic disorders
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... DDX: Rule Out Secondary ... Workup: • Complete ... blood count with differential
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... nodosum • Immune hemolytic ... anemia • Pain ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate
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