14 results
Medications associated with neuroleptic malignant syndrome

First-generation and second-generation antipsychotics are dopamine receptor antagonists, which produce a
which produce a state ... after years of treatment ... #Diagnosis #Differential ... #Medications #Drugs ... #Causes
A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins.

There are 5
toxidrome is a syndrome ... set of symptoms) caused ... barbituates, “Z-drugs ... antihistamines #Diagnosis ... Toxicology #Toxidromes #Comparison
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
: Drugs: Ecstasy ... Neuroleptic malignant syndrome ... ; Serotonin syndrome ... #Hyperthermia #comparison ... #diagnosis #management
Neurological Side Effects of Antipsychotic Drugs
Acute dystonia - Spasm of muscles of tongue, face, neck, back
Antiparkinsonian agents are diagnostic ... rigidity, fever, unstable ... tremor ("rabbit syndrome ... months or years of treatment ... #SideEffects #pharmacology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
- Differential Diagnosis ... Drugs (Statins), ... per day until stable ... Management #Summary #causes ... #treatment
Shock - Differential Diagnosis Framework
MAP = CO x SVR
Hypovolemic (↓ Intravascular volume):
 • Hemorrhage, dehydration due
- Differential Diagnosis ... findings based on cause ... anaphylaxis, release syndrome ... adrenal crisis, drugs ... #table #comparison
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Management Summary Causes ... - Toxins - Drugs ... per day until stable ... #Management #causes
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... life-threatening • Treatment ... druginduced #lupus #sle #comparison ... #table #rheumatology ... #diagnosis #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... Dyskeratosis congenita • Drugs ... - Cytotoxic drugs ... aplastic anemia Treatment ... oncology #hematology #diagnosis
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
/ hypoxemia -> focus ... circulation If drugs ... before beginning treatment ... - Compartment syndrome ... Alcohol • Type B2: Drugs