8 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
that disrupts immune ... ↑ sIL-2R >2400 Ul ... +: Virus (EBV, CMV ... or biologics (CMV ... deficiency, Drugs
IDSA Recommendations for Treating Cytomegalovirus Infections in HIV-AIDS
Preventing CMV Disease:
 • CMV end-organ disease is best
IDSA Recommendations ... intraocular levels of drug ... infection until steady state ... #opportunistic ... infections #HIVAIDS #pharmacology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Immune Reconstitution ... • A state of hyperinflammatory ... reconstituted immune ... keratitis, iritis • CMV ... unintentional weight loss, nausea
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
mutations) • Immune ... and petechiae Causes ... - Cytotoxic drugs ... - EBV - CMV ... aplastic anemia Treatment
IDSA Recommendations for Preventing and Treating Disseminated Mycobacterium Avium Complex in HIV-AIDS
Preventing 1st Episode of Disseminated
IDSA Recommendations ... please refer to Table ... #Prevention #Treatment ... #management #opportunistic ... infections #HIVAIDS #pharmacology
IDSA Recommendations for Preventing and Managing Microsporidiosis in HIV-AIDS
Preventing Chronic Microsporidiosis:
 • Because chronic microsporidiosis occurs
IDSA Recommendations ... optimize ART with immune ... Gastrointestinal Infections Caused ... #management #opportunistic ... infections #HIVAIDS #pharmacology
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS
Treating LTBI (to prevent TB disease)
Indications:
IDSA Recommendations ... Please refer to the table ... Tuberculosis #TB #IDSA ... #management #opportunistic ... infections #HIVAIDS #pharmacology
IDSA Recommendations for Preventing and Treating Histoplasma Capsulatum Infections in HIV-AIDS
Indications for Initiating Primary Prophylaxis:
 •
IDSA Recommendations ... with ARV (see Table ... #Prevention #Treatment ... #management #opportunistic ... infections #HIVAIDS #pharmacology