7 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
↑ sIL-2R >2400 Ul ... +: Virus (EBV, CMV ... ..), Bacteria (Mycobacteria ... Drugs, Unknown cause ... Treatment: •
IDSA Recommendations for Treating Cytomegalovirus Infections in HIV-AIDS
Preventing CMV Disease:
 • CMV end-organ disease is best
whenever feasible, treatment ... effective for treatment ... control of the infection ... until steady state ... #HIVAIDS #pharmacology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... - EBV - CMV ... Parvovirus B19 • Mycobacteria ... Cytomegalovirus (CMV ... aplastic anemia Treatment
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
• A state of hyperinflammatory ... six months of treatment ... organizing PNA • Mycobacterium ... keratitis, iritis • CMV ... unintentional weight loss, nausea
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS
Treating LTBI (to prevent TB disease)
Indications:
Recommendations for Treating Mycobacterium ... Tuberculosis Infection ... Please refer to the table ... #LTBI #Mycobacterium ... #HIVAIDS #pharmacology
IDSA Recommendations for Preventing and Treating Disseminated Mycobacterium Avium Complex in HIV-AIDS
Preventing 1st Episode of Disseminated
Treating Disseminated Mycobacterium ... please refer to Table ... IDSA #Prevention #Treatment ... opportunistic #infections ... #HIVAIDS #pharmacology
IDSA Recommendations for Preventing and Treating Histoplasma Capsulatum Infections in HIV-AIDS
Indications for Initiating Primary Prophylaxis:
 •
Histoplasma Capsulatum Infections ... histoplasmosis (>10 cases ... with ARV (see Table ... IDSA #Prevention #Treatment ... #HIVAIDS #pharmacology