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management idsa opportunistic prevention diagnosis anemia aplastic aviumcomplex capsulatum differential hematology hemophagocytic histoplasma histoplasmosis hlh immune inflammatory iris ltbi lymphohistiocytosis
IDSA Recommendations for Treating Cytomegalovirus Infections in HIV-AIDS Preventing CMV Disease: • CMV end-organ disease is best
Recommendations for Treating Cytomegalovirus ... until steady state ... once daily #Cytomegalovirus ... opportunistic #infections ... #HIVAIDS #pharmacology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
↑ sIL-2R >2400 Ul ... +: Virus (EBV, CMV ... ..), Bacteria (Mycobacteria ... Drugs, Unknown cause ... Treatment: •
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... - EBV - CMV ... Parvovirus B19 • Mycobacteria ... • Cytomegalovirus ... aplastic anemia Treatment
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
• A state of hyperinflammatory ... six months of treatment ... organizing PNA • Mycobacterium ... keratitis, iritis • CMV ... unintentional weight loss, nausea
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS Treating LTBI (to prevent TB disease) Indications:
Recommendations for Treating Mycobacterium ... Tuberculosis Infection ... Please refer to the table ... #LTBI #Mycobacterium ... #HIVAIDS #pharmacology
IDSA Recommendations for Preventing and Treating Disseminated Mycobacterium Avium Complex in HIV-AIDS Preventing 1st Episode of Disseminated
Treating Disseminated Mycobacterium ... please refer to Table ... IDSA #Prevention #Treatment ... opportunistic #infections ... #HIVAIDS #pharmacology
IDSA Recommendations for Preventing and Treating Histoplasma Capsulatum Infections in HIV-AIDS Indications for Initiating Primary Prophylaxis: •
Histoplasma Capsulatum Infections ... histoplasmosis (>10 cases ... with ARV (see Table ... IDSA #Prevention #Treatment ... #HIVAIDS #pharmacology
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