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diagnosis betadglucan galactomannan management antibiotics aspergillus biomarkers comparison ebm falsepositives febrile infant infections infectiousdiseases laboratory lp mycoses pediatrics peds stratification
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
& Specificity: ... & Specificity ... useful in high risk ... post-2010 almost never ... Frozen ice-pops (in setting
The Febrile Infant Step-by-Step Algorithm This is an algorithm developed by European emergency physicians to identify low-risk
to identify low-risk ... pubmed/27382134 Sensitivity ... and specificity ... Febrile #Infant #StepByStep ... Stratification #Fever
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
Galactomannan Testing ... Sensitivity Specificity ... 96% • Higher specificity ... useful in high risk ... post-2010 almost never
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
antigen assay has a sensitivity ... and specificity ... MUCORMYCOSIS • Risk ... Urinary antigen testing ... Encapsulated yeast • At risk
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