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diagnosis fungal stratification betadglucan febrile galactomannan infant management pediatrics peds antibiotics aspergillus biomarkers comparison evaluation falsepositives infections infectiousdiseases laboratory lp
Validation of the “Step-by-Step” Approach in the Management of Young Febrile Infants Visual Abstract by Dr. Kirsty
pubmed/27382134 #EBM ... Peds #Pediatrics #VisualAbstract ... #StepByStep #Algorithm ... Febrile #Infant #Risk ... Stratification #Fever
The Febrile Infant Step-by-Step Algorithm This is an algorithm developed by European emergency physicians to identify low-risk
to identify low-risk ... Sensitivity and specificity ... 46.9% #Diagnosis #EBM ... Febrile #Infant #StepByStep ... Stratification #Fever
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
or family - Ever ... event, follow ACC algorithm ... unless prior heart/lung ... surgery Stress Testing ... preoperative stress testing
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Sensitivity & Specificity ... useful in high risk ... Clav (may be + as long ... post-2010 almost never ... Frozen ice-pops (in setting
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
Galactomannan Testing ... Sensitivity Specificity ... 96% • Higher specificity ... useful in high risk ... result in + as long
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
sensitivity and specificity ... MUCORMYCOSIS • Risk ... Urinary antigen testing ... change in the lungs ... nails, bronchi, lungs
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