781 results
Adrenal Insufficiency Diagnosis Algorithm
Clinical features: 
 - Weight loss, anorexia, Weakness, fatigue, GI distress
 - Hypotension,
Adrenal Insufficiency ... due to high ACTH stimulating ... seen in PRIMARY adrenal ... with cosyntropin stimulation ... #Cosyntropin #Stimulation
Adrenal Insufficiency Algorithm - Cosyntropin Stimulation Test
T-1m: Baseline cortisol drawn
T0: 250 µg cosyntropin given IV
T30m: Repeat
Adrenal Insufficiency ... - Cosyntropin Stimulation ... BCM_InternalMed #Adrenal ... #Cosyntropin #Stimulation
Primary Adrenal Insufficiency:
 • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
Insufficiency: • ACTH stimulation ... production • CRH stimulation ... long-term lack of stimulation ... chronic lack of stimulation ... by ACTH • CRH stimulation
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Adrenal Insufficiency ... hormone (ACTH) stimulation ... Cortisol Response - Adrenal ... ACTH - Primary adrenal ... ACTH - Secondary adrenal
Primary vs Secondary Adrenal Insufficiency - Pathophysiology
Primary AI = adrenal glands themselves are the problem. This
Primary vs Secondary Adrenal ... Pathophysiology Primary AI = adrenal ... leads to limited adrenal ... stimulation, thus ... Primary #Secondary #Adrenal
Algorithm for the diagnosis of adrenal insufficiency (AI). The standard cosyntropin stimulation test (CST) may be
the diagnosis of adrenal ... standard cosyntropin stimulation ... evaluation of adrenal
Diagnosis Adrenal Insufficiency - Algorithm

Step 1) Screening Test: 6-8AM Cortisol Level
 - Early morning cortisol levels
Diagnosis Adrenal ... Test: Cosyntropin Stimulation ... determines if the adrenal ... gland) #Adrenal ... Diagnosis #ACTH #Stimulation
Adrenal Insufficiency Diagnosis Algorithm
Test 1: Baseline AM Cortisol 
 - Beware of major normal value
 -
Adrenal Insufficiency ... ) Test 2: ACTH Stimulation ... BCM_InternalMed #Adrenal
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH

Early am cortisol < 3
Adrenal Insufficiency ... indicates normal adrenal ... tertiary AI #Adrenal ... Algorithm #ACTH #Stimulation
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Primary Adrenal ... Damage of the adrenal ... aldosterone Causes of Adrenal ... present - ACTH stimulation ... HYDROCORTISONE #Primary #adrenal