49 results
Diagnosing Vitamin B12 and/or Folate Deficiency

It turns out that simply measuring serum levels of B12 or
and/or Folate Deficiency ... with low B12 stores ... normal tissue stores ... tissue folate stores ... Diagnosis #Nutrition #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... Non malignant hematologic ... effect following treatment ... malignancy • Iron deficiency ... Thrombocytosis #Differential
Etiologies of Folate Deficiency
 • Decreased dietary intake - uncommon in this era
 • Increased requirements
Etiologies of Folate Deficiency ... mobilize folate stores ... depleted tissue stores ... #FolicAcid #differential ... #diagnosis #hematology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
severe, ADAMTS13 deficiency ... PLEX and RTX • Short-term ... Thrombocytopenic #Purpura #management ... #treatment #rheumatology ... #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Diagnosis and Management ... disorders • Shear stress-induced ... Syndrome #Diagnosis #Management ... #treatment #hematology ... #differential
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Allopecia - Differential ... Lithium • Stress ... texture at bald spots ... loss #alopecia #Differential ... #Diagnosis #dermatology
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
Diffuse and Focal) Differential ... • Lithium - Stress ... Psychological stress ... HairLoss #Alopecia #dermatology ... #Differential #
Iron Deficiency Anemia (IDA)
Tests:
 • MCV/RBC - RBC ↓ in proportion to the ↓ in hemoglobin
Iron Deficiency ... total body iron stores ... DharSaty #Iron #Deficiency ... Fe #diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... → Refer to hematology ... Acute hemolysis, deficiency ... Rebound effect from treatment ... Thrombocytosis #Platelets #Differential
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Differential Diagnosis ... Disease • GH Deficiency ... • IGF-I Deficiency ... Panhypopituitarism Treatment ... #ShortStature #Differential