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diagnosis differential hepatology hematology management product reactions acidosis algorithm bloodsmear borrelia chemistry cholestatic classification clinical elevation enzymes function hepatitis hepatocellular
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... ) - Causes of Hepatocellular ... Liver Injury ... #Enzymes #LFTs ... #Cholestatic #Transaminitis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... Hepatopathy • Acute ... injury) • Ischemic ... Function #Tests #LFTs ... Diagnosis #hepatology #transaminitis
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... Injury Transaminase ... > 20x normal - Acute ... #Patterns #Liver ... #LFTs #transaminitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... injury < 26 weeks ... intestines, White blood ... differential #Hepatology #transaminitis ... #LFTs #RValue #
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Algorithm Vascular Causes ... of Acute Liver ... Liver Injury: ... intestines, white blood
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
removal from the blood ... or renal injury ... cardiac output - Acute ... peritonitis - Acute ... Injury: • Reduced
Borrelia recurrentis on Peripheral Blood Smear 23M Somali refugee recently arrived w/severe abd pain, confusion and fever
on Peripheral Blood ... Mild LFT ↑ This ... Specific organ injury ... smear, acute and ... often experience acute
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Acute Hemolytic ... Causes purpura & ... Transfusion Related Acute ... Lung Injury (TRALI ... eruptions, diarrhea, liver
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... Causes purpura & ... Transfusion Related Acute ... Lung Injury (TRALI ... eruptions, diarrhea, liver
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